Results 11 to 20 of about 2,593,342 (293)
SUMO: regulating the regulator.
Cell division, 2006 Post-translational modifiers of the SUMO (Small Ubiquitin-related Modifier) family have emerged as key regulators of protein function and fate. While the past few years have seen an enormous increase in knowledge on SUMO enzymes, substrates, and consequences of modification, regulation of SUMO conjugation is far from being understood. This brief review
Bossis, G., Melchior, F.
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Scientific Reports, 2017 The anuran Rhinella spinulosa is distributed along the Andes Range at altitudes that undergo wide daily and seasonal variation in temperature. One of the populations inhabits geothermal streams, a stable environment that influences life history traits ...
Luis Pastenes +11 more
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Delayed Liver Regeneration after Partial Hepatectomy in Aged Nos2 Knockout Mice
Cell Journal, 2017 Objective Patients over 60 years of age have higher mortality and morbidity after major liver resections. Nitric oxide (NO) derived from the catalytic activity of Nos2 plays a beneficial role in liver regeneration (LR) after partial hepatectomy (PH). In
Deming Li +6 more
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EPJ Web of Conferences, 2017 Pulse height distributions were measured using a CdZnTe detector inside a lead collimator to investigate main source producing high dose rates above the shield plugs of Unit 3 at Fukushima Daiichi Nuclear Power Station.
Hiratama Hideo +5 more
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Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models
EMBO Molecular Medicine, 2021 Some antibacterial therapies entail sequential treatments with different antibiotics, but whether this approach is optimal for anti‐cancer tyrosine kinase inhibitors (TKIs) remains open. EGFR mutations identify lung cancer patients who can derive benefit
Ilaria Marrocco +11 more
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DNA methylation dynamics in the rat EGF gene promoter after partial hepatectomy
Genetics and Molecular Biology, 2014 Epidermal growth factor (EGF), a multifunctional growth factor, is a regulator in a wide variety of physiological processes. EGF plays an important role in the regulation of liver regeneration.
Deming Li +3 more
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BMC Pulmonary Medicine, 2019 Background E-cigarette use prevalence has grown rapidly in the US. Despite the popularity of these products, few acute exposure toxicity studies exist, and studies on long-term pulmonary health effects are limited.
Albert D. Osei +8 more
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ExOrthist: a tool to infer exon orthologies at any evolutionary distance
Genome Biology, 2021 Several bioinformatic tools have been developed for genome-wide identification of orthologous and paralogous genes. However, no corresponding tool allows the detection of exon homology relationships.
Yamile Márquez +7 more
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Functional Characteristics of Gene Expression Motifs with Single and Dual Strategies of Regulation [PDF]
Biomed. Phys. Eng. Express, 2 , 025009(2016), 2016 Transcriptional regulation by transcription factors and post-transcriptional regulation by microRNAs constitute two major modes of regulation of gene expression. While gene expression motifs incorporating solely transcriptional regulation are well investigated, the dynamics of motifs with dual strategies of regulation, i.e., both transcriptional and ...
arxiv +1 more source
CK2 and PML: Regulating the Regulator [PDF]
Cell, 2006 The PML protein induces senescence, and, upon oncogenic stress, its absence promotes cellular transformation. In this issue of Cell, Scaglioni et al. (2006) show that phosphorylation of PML by CK2, a kinase frequently activated in human cancers, promotes PML degradation.
Lallemand-Breitenbach, V., de Thé, H.
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