Results 11 to 20 of about 6,082,428 (365)
Regulating the Regulators [PDF]
Science, 2003 Activation of the immune system in response to pathogens carries with it the possibility of a harmful autoimmune response. In their Perspective, Powrie and Maloy discuss a newly recognized group of regulatory T cells (T) that fine tune protective antimicrobial immune responses in order to minimize harmful immune pathology ( Hori et ...
Powrie, F, Maloy, K
+8 more sources
The Internet: To Regulate or Not Regulate? [PDF]
SSRN Electronic Journal, 2018 This submission was prepared in response to a call for evidence launched on 29 March 2018 by the House of Lords Select Committee on Communications entitled “The Internet: To Regulate or Not to Regulate?”. The broad inquiry sought evidence to explore how the regulation of the internet should be improved, and to consider whether online platforms which ...
Rachel Allsopp +5 more
openaire +2 more sources
BMJ, 2002 The British government has plans for a new council to oversee the eight statutory regulators of health professionals (see box). The plans went out for consultation in the summer1 and are included in a bill currently before parliament.2 Proposals for the new overarching council were mooted in the NHS plan and backed by the recent Kennedy report into ...
Belinda Finlayson, Steve Dewar
openaire +4 more sources
SUMO: regulating the regulator.
Cell division, 2006 Post-translational modifiers of the SUMO (Small Ubiquitin-related Modifier) family have emerged as key regulators of protein function and fate. While the past few years have seen an enormous increase in knowledge on SUMO enzymes, substrates, and consequences of modification, regulation of SUMO conjugation is far from being understood. This brief review
Bossis, G., Melchior, F.
openaire +5 more sources
The EU General Data Protection Regulation (GDPR)
, 2020 This new book provides an article-by-article commentary on the new EU General Data Protection Regulation. Adopted in April 2016 and applicable from May 2018, the GDPR is the centrepiece of the recent reform of the EU regulatory framework for protection ...
semanticscholar +1 more source
EPJ Web of Conferences, 2017 Pulse height distributions were measured using a CdZnTe detector inside a lead collimator to investigate main source producing high dose rates above the shield plugs of Unit 3 at Fukushima Daiichi Nuclear Power Station.
Hiratama Hideo +5 more
doaj +1 more source
BMC Plant Biology, 2022 Background Abscisic acid receptors (ABR) involve transduction of the ABA signaling in plants, impacting largely on stress-defensive physiological processes and plant osmotic stress response. In this study, we characterized TaPYL4, a gene of ABR family in
Yanyang Zhang +6 more
doaj +1 more source
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
International Journal of Molecular Sciences, 2019 The NLRP3 inflammasome is a critical component of the innate immune system that mediates caspase-1 activation and the secretion of proinflammatory cytokines IL-1β/IL-18 in response to microbial infection and cellular damage.
N. Kelley +3 more
semanticscholar +1 more source
DNA methylation dynamics in the rat EGF gene promoter after partial hepatectomy
Genetics and Molecular Biology, 2014 Epidermal growth factor (EGF), a multifunctional growth factor, is a regulator in a wide variety of physiological processes. EGF plays an important role in the regulation of liver regeneration.
Deming Li +3 more
doaj +1 more source
Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models
EMBO Molecular Medicine, 2021 Some antibacterial therapies entail sequential treatments with different antibiotics, but whether this approach is optimal for anti‐cancer tyrosine kinase inhibitors (TKIs) remains open. EGFR mutations identify lung cancer patients who can derive benefit
Ilaria Marrocco +11 more
doaj +1 more source