Results 151 to 160 of about 1,659,012 (319)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Dynamic 3D chromatin organization and epigenetic regulation of gene expression in peanut nodules. [PDF]

J Integr Plant Biol
Wang L, Mai C, He S, Niu B, Jia G, Yang T, Xu Y, Ren M, Zhao X, Liu X, Kong Z.   +10 more
europepmc   +1 more source

Regulation of Gene Expression by m6Am RNA Modification. [PDF]

Int J Mol Sci, 2023
Cesaro B, Tarullo M, Fatica A.
europepmc   +1 more source

Altered regulation of aquaporin gene expression in allergen and IL-13-induced mouse models of asthma

, 2009
Carissa M. Krane, Bijia Deng, Venkateshwar Mutyam, C.A. McDonald, Stephen Pazdziorko, Lawrence E. Mason, Samuel Goldman, Marion T. Kasaian, Divya Chaudhary, Cara Williams, Melisa W-Y. Ho   +10 more
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Influence of DNA methylation and chromatin accessibility on regulation of gene expression during <i>Trichomonas vaginalis-</i>host cell interaction. [PDF]

mBio
Muñoz D, Lizarraga A, Johnson PJ, Strobl-Mazzulla PH, de Miguel N.   +4 more
europepmc   +1 more source

Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development. [PDF]

PLoS One, 2023
Cowell LM, King M, West H, Broadsmith M, Genever P, Pownall ME, Isaacs HV.   +6 more
europepmc   +1 more source

Posttranscriptional regulation of ectoderm-specific gene expression in early sea urchin embryos [PDF]

, 1992
Michael L. Gagnon, Lynne M. Angerer, Robert C. Angerer   +2 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Applying the brakes to transcription: regulation of gene expression by RNA polymerase pausing. [PDF]

J Bacteriol
Jayasinghe OT, Babitzke P.
europepmc   +1 more source