Results 61 to 70 of about 1,600,466 (167)

Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss

npj Aging and Mechanisms of Disease, 2020
Age-related hearing loss (AHL) is a progressive sensorineural hearing loss in elderly people. Although no prevention or treatments have been established for AHL, recent studies have demonstrated that oxidative stress is closely related to pathogenesis of
Tetsuya Oishi, Daisuke Matsumaru, Nao Ota, Hiroshi Kitamura, Tianxiang Zhang, Yohei Honkura, Yukio Katori, Hozumi Motohashi   +7 more
doaj   +1 more source

Six Highly Conserved Targets of RNAi Revealed in HIV-1-Infected Patients from Russia Are Also Present in Many HIV-1 Strains Worldwide

Molecular Therapy: Nucleic Acids, 2017
RNAi has been suggested for use in gene therapy of HIV/AIDS, but the main problem is that HIV-1 is highly variable and could escape attack from the small interfering RNAs (siRNAs) due to even single nucleotide substitutions in the potential targets.
Olga V. Kretova, Daria M. Fedoseeva, Maria A. Gorbacheva, Natalya M. Gashnikova, Maria P. Gashnikova, Nataliya V. Melnikova, Vladimir R. Chechetkin, Yuri V. Kravatsky, Nickolai A. Tchurikov   +8 more
doaj   +1 more source

Author Correction: Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

Nature Communications, 2022
Federico Pelisch, Remi Sonneville, Ehsan Pourkarimi, Ana Agostinho, J. Julian Blow, Anton Gartner, Ronald T. Hay   +6 more
doaj   +1 more source

Efficient analysis of mammalian polysomes in cells and tissues using Ribo Mega-SEC

eLife, 2018
We describe Ribo Mega-SEC, a powerful approach for the separation and biochemical analysis of mammalian polysomes and ribosomal subunits using Size Exclusion Chromatography and uHPLC.
Harunori Yoshikawa, Mark Larance, Dylan J Harney, Ramasubramanian Sundaramoorthy, Tony Ly, Tom Owen-Hughes, Angus I Lamond   +6 more
doaj   +1 more source

LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis

Nature Communications, 2018
Chromosome segregation and genome maintenance require the removal of DNA bridges that link chromosomes just before cells divide. Here the authors show that the LEM-3/Ankle1 nuclease processes DNA bridges before cells divide and define a previously ...
Ye Hong, Remi Sonneville, Bin Wang, Viktor Scheidt, Bettina Meier, Alexander Woglar, Sarah Demetriou, Karim Labib, Verena Jantsch, Anton Gartner   +9 more
doaj   +1 more source

Regulation of Gene Expression in Cancer-An Overview. [PDF]

Cells, 2022
Ferlier T, Coulouarn C.
europepmc   +1 more source

Plant nuclear envelope as a hub connecting genome organization with regulation of gene expression. [PDF]

Nucleus, 2023
Tang Y.
europepmc   +1 more source

microRNA-dependent regulation of gene expression in GABAergic interneurons. [PDF]

Front Cell Neurosci, 2023
Kołosowska KA, Schratt G, Winterer J.
europepmc   +1 more source

Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development. [PDF]

PLoS One, 2023
Cowell LM, King M, West H, Broadsmith M, Genever P, Pownall ME, Isaacs HV.   +6 more
europepmc   +1 more source

Dynamic 3D chromatin organization and epigenetic regulation of gene expression in peanut nodules. [PDF]

J Integr Plant Biol
Wang L, Mai C, He S, Niu B, Jia G, Yang T, Xu Y, Ren M, Zhao X, Liu X, Kong Z.   +10 more
europepmc   +1 more source