Results 101 to 110 of about 6,497,314 (414)
Inferring cell-specific lncRNA regulation with single-cell RNA-sequencing data in the developing human neocortex [PDF]
Long non-coding RNAs (lncRNAs) are important regulators to modulate gene expression and cell proliferation in the developing human brain. Previous methods mainly use bulk lncRNA and mRNA expression data to study lncRNA regulation. However, to analyze lncRNA regulation regarding individual cells, we focus on single-cell RNA-sequencing (scRNA-seq) data ...
arxiv
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
The 2003 Money Laundering Regulations [PDF]
The Money Laundering Regulations 2003 came into force in the early part of 2004 in order to implement the EU Second Money Laundering Directive. They are much wider-ranging than the 1993 Regulations, which had preceded them: in addition to banks and ...
Alexander, R.C.H.
core +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Purpose - The purpose of this paper is to analyze in theory and practice the extent and ways the role of regulators in collaborative regulatory systems differs from their roles in more traditional, state-led regulatory systems. Methodology/Approach/Design - The descriptive and analytical methodology of this paper is supported by primary and ...
openaire +4 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
We discuss several approaches to motivic complexes and explicit constructions of the regulator maps from the motivic complexes to Deligne complexes.
openaire +2 more sources
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Finite-dimensional output feedback regulator for a mono-tubular heatexchanger process [PDF]
In this work, we consider the output tracking and disturbance rejection problems of a mono-tubular heat exchanger process and a novel finite-dimensional output feedback regulator is developed. In the proposed output feedback regulator design, measurements available for the regulator do not belong to the set of controlled outputs. In other words, design
arxiv
Flexible Labor Regulations and Informality in Egypt
Do more flexible labor market regulations reduce informal employment in formal firms? This paper examines the effects of changes in labor regulations on the incidence of formal employment. Using the case of Egypt, we study the effects of the introduction
J. Wahba, R. Assaad
semanticscholar +1 more source