Results 51 to 60 of about 269,212 (236)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Неврология, нейропсихиатрия, психосоматика, 2013 The time course of changes in the parameters reflecting the status of different components of the body’s regulatory systems was studied in 125patients with hemispheric ischemic stroke via comprehensive evaluation of the hypothalamo-pituitary axes and ...
Aleksandr Mikhailovich Dolgov +1 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Evaluation of stress resistance among young men after autogenous training
Кубанский научный медицинский вестник, 2014 At 60 students - two weeks prior to the first final employment and before the first final employment carried out test of cardiorespiratory synchronism. On dynamics of the regulation-adaptive status determined a level stress resistance.
O. M. Drobysheva, V. G. Abushkevich
doaj
Medical Journal of the Russian Federation, 2017 The purpose. To compare efficiency of application of Bisoprosol and Nebivolol in patients with paroxysmal supra-ventricular tachycardia against the background of hypertension disease considering their effect on regulatory adaptive status.Materials and method.
N. M Nazhalkina +2 more
openaire +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Кубанский научный медицинский вестник, 2016 48 patients with various forms of chronic periodontitis before and after treatment were carried out sample cardiorespiratory synchronism, the index was calculated regulatory-adaptive status, as it was determined by the regulatory-adaptive capabilities of
A. O. Serobian +5 more
doaj
Advances in Dietary Restriction on the Regulation of Organismal Immune Function [PDF]
Zhongguo quanke yixueNutritional status may influence the immune response, and dietary restriction (DR) , as an important dietary intervention, has been shown to potentially play an important regulatory role in the activation and effector functioning of immune cells and is ...
GAO Jiaxin, ZHOU Ruihan, WANG Fangfang, PANG Rizhao, ZHANG Anren
doaj +1 more source