New insights into regulatory cell death and acute pancreatitis [PDF]
Heliyon, 2023 Acute pancreatitis (AP) may be associated with both local and systemic complications. Although it is usually self-limiting, up to 20% of patients develop severe acute pancreatitis (SAP), which leads to systemic inflammatory response syndrome (SIRS) and ...
Hongyao Li +3 more
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A regulatory network controlling ovarian granulosa cell death
Cell Death Discovery, 2023 Follicular atresia triggered by granulosa cell (GC) apoptosis severely reduces female fertility and accelerates reproductive aging. GC apoptosis is a complex process regulated by multiple factors, regulatory axes, and signaling pathways.
Liu Yang +5 more
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Programmed Cell Death: Complex Regulatory Networks in Cardiovascular Disease [PDF]
Frontiers in Cell and Developmental Biology, 2021 Abnormalities in programmed cell death (PCD) signaling cascades can be observed in the development and progression of various cardiovascular diseases, such as apoptosis, necrosis, pyroptosis, ferroptosis, and cell death associated with autophagy ...
Liuhua Zhou +8 more
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Research Progress of Regulatory Cell Death in Coronary Microembolization. [PDF]
Int J Med SciCoronary microembolization (CME) is defined as atherosclerotic plaque erosion, spontaneous rupture, or rupture of the plaque while undergoing interventional therapy resulting in the formation of tiny emboli that obstruct the coronary microcirculatory system.
Chang C +5 more
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Alternative Cell Death Pathways and Cell Metabolism [PDF]
International Journal of Cell Biology, 2013 While necroptosis has for long been viewed as an accidental mode of cell death triggered by physical or chemical damage, it has become clear over the last years that necroptosis can also represent a programmed form of cell death in mammalian cells.
Simone Fulda
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Unraveling the regulatory cell death pathways in gastric cancer: a multi-omics study [PDF]
Frontiers in PharmacologyGastric cancer (GC) is a prevalent form of cancer worldwide and has a high death rate, with less than 40% of patients surviving for 5 years. GC demonstrates a vital characteristic of evading regulatory cell death (RCD).
Jiazheng Sun +4 more
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Regulatory approval of photoimmunotherapy: photodynamic therapy that induces immunogenic cell death [PDF]
OncoImmunology, 2020 In September 2020, the Japanese government approved cetuximab saratolacan (previously known as RM-1929, commercial name: Akalux) for the treatment of unresectable locally advanced or recurrent head and neck cancer.
Lígia C. Gomes-da-Silva +2 more
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Unraveling the role of regulatory cell death in sepsis: an integrated analysis of bulk and single-cell sequencing data [PDF]
PeerJBackground Sepsis is a life-threatening condition characterized by systemic inflammation and dysfunction of multiple organs. Recently, regulatory cell death (RCD) has emerged as a distinct pathological feature and serve as a potential source of ...
Susu Cao +5 more
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Regulatory T Cells Resist Cyclosporine-Induced Cell Death via CD44-Mediated Signaling Pathways
International Journal of Cell Biology, 2015 Cyclosporine A (CSA) is an immunosuppressive agent that specifically targets T cells and also increases the percentage of pro-tolerogenic CD4+Foxp3+ regulatory T cells (Treg) through unknown mechanisms.
Shannon M. Ruppert +3 more
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[Research progress on the regulatory cell death of osteoblasts in periodontitis]. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue BanPeriodontitis is a chronic inflammatory disease characterized by progressive destruction of alveolar bone. The most critical mechanism underlying alveolar bone destruction is the imbalance of bone homeostasis, where osteoblast-mediated bone matrix synthesis plays an important role in regulating bone homeostasis.
Bao J, Wei Y, Chen L.
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