Results 101 to 110 of about 1,021,844 (200)

Collective Classification of Textual Documents by Guided Self-Organization in T-Cell Cross-Regulation Dynamics

, 2011
We present and study an agent-based model of T-Cell cross-regulation in the adaptive immune system, which we apply to binary classification. Our method expands an existing analytical model of T-cell cross-regulation (Carneiro et al. in Immunol Rev 216(1):
Abi-Haidar, Alaa, Rocha, Luis M.
core   +1 more source

Regulation of apoptosis, ferroptosis, and pyroptosis mediated by acetylation

Cell Death Discovery
Acetylation is an important post-translational modification (PTM) of proteins and plays critical roles in multiple biological processes. The modes of cell death represent different pathways leading to the final outcome of “death” for the cell, with ...
Weijie Lu, Yaoting Deng, Mengyang Liu, Yujie Hu, Kang Yang, Bowen Wang, Yanling Li, Gang Wang, Li Ma, Jiajia Liu, Yaohui Xie, Qianrong Li, Ai Liu, Xiubin Zhang, Ping Xie   +14 more
doaj   +1 more source

Application of Regulatory Cell Death in Cancer: Based on Targeted Therapy and Immunotherapy. [PDF]

Front Immunol, 2022
Qi X, Li Q, Che X, Wang Q, Wu G.
europepmc   +1 more source

Autophagy and autophagic cell death in sepsis: friend or foe?

Journal of Intensive Care
In sepsis, inflammation, and nutrient deficiencies endanger cellular homeostasis and survival. Autophagy is primarily a mechanism of cellular survival under fasting conditions.
Toshiaki Iba, Julie Helms, Cheryl L. Maier, Ricard Ferrer, Jerrold H. Levy   +4 more
doaj   +1 more source

Modulatory Effects of Regulated Cell Death: An Innovative Preventive Approach for the Control of Mastitis

Cells
Mastitis is a common disease worldwide that affects the development of the dairy industry due to its high incidence and complex etiology. Precise regulation of cell death and survival plays a critical role in maintaining internal homeostasis, organ ...
Xiaojing Xia, Pengfei Ren, Yilin Bai, Jingjing Li, Huihui Zhang, Lei Wang, Jianhe Hu, Xinwei Li, Ke Ding   +8 more
doaj   +1 more source

Mdivi-1, a mitochondrial fission inhibitor, modulates T helper cells and suppresses the development of experimental autoimmune encephalomyelitis. [PDF]

, 2019
BACKGROUND: Unrestrained activation of Th1 and Th17 cells is associated with the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE).
Chai, Zhi, Ciric, Bogoljub, Curtis, Mark T., Guo, Min-Fang, Li, Rui-Lan, Li, Yan-Hua, Ma, Cun-Gen, Rostami, A. M., Song, Guo-Bin, Sun, Man-Luan, Thome, Rodolfo, Xu, Fang, Zhang, Guang-Xian   +12 more
core   +1 more source

Exploring plant tolerance to biotic and abiotic stresses [PDF]

, 2007
Plants are exposed to many stress factors, such as drought, high salinity or pathogens, which reduce the yield of the cultivated plants or affect the quality of the harvested products. Arabidopsis thaliana was used as a model plant to study the responses
Karim, Sazzad
core  

Unraveling the regulatory cell death pathways in pulmonary fibrosis

Abstract Background Idiopathic pulmonary fibrosis (IPF) is one of the interstitial lung diseases (ILDs) with poor prognosis. Multiple regulated cell death (RCD) pathways are involved in regulating the progression of pulmonary fibrosis at different stages.
Jiazheng Sun, Yulan Zeng
openaire   +1 more source

Therapeutic strategies of targeting non-apoptotic regulated cell death (RCD) with small-molecule compounds in cancer

Acta Pharmaceutica Sinica B
Regulated cell death (RCD) is a controlled form of cell death orchestrated by one or more cascading signaling pathways, making it amenable to pharmacological intervention.
Xin Jin, Wenke Jin, Linlin Tong, Jia Zhao, Lan Zhang, Na Lin   +5 more
doaj   +1 more source

RCDdb: A manually curated database and analysis platform for regulated cell death

Computational and Structural Biotechnology Journal
Regulated cell death is a pivotal regulatory mechanism governing the development and homeostasis of multicellular organisms. A comprehensive understanding of RCD's regulatory mechanisms is crucial for developing novel therapeutic strategies against ...
Xiaopeng Wang, Qing Wang, Jun Zhao, Jiaxin Chen, Ruo Wu, Juanjuan Pan, Jiaxin Li, Zechang Wang, Yongchang Chen, Wenting Guo, Yuanyuan Li   +10 more
doaj   +1 more source