Results 161 to 170 of about 1,021,844 (200)

Cell volume regulatory mechanisms in apoptotic cell death

Herz, 1999
One of the hallmarks of apoptosis is cell shrinkage, which--at constant extracellular osmolarity--requires a decrease of cellular osmolarity. Moreover, apoptosis can be elicited by increase of extracellular osmolarity and the resistance of cells towards apoptosis correlates with their ability to regulate their volume in hypertonic environment.
F, Lang, A C, Uhlemann, A, Lepple-Wienhues, I, Szabo, D, Siemen, B, Nilius, E, Gulbins   +6 more
openaire   +4 more sources

Regulatory Roles of JNK in Programmed Cell Death

Journal of Biochemistry, 2004
Programmed cell death or apoptosis is the regulatory mechanism for removing unneeded cells during animal development and in tissue homeostasis. Perturbation of the cell death mechanisms leads to various disorders, including neurodegenerative diseases, immunodeficiency diseases, and tumors.
Hiroshi, Kanda, Masayuki, Miura
openaire   +2 more sources

Bistability regulates TNFR2-mediated survival and death of T-regulatory cells

Journal of Biological Physics, 2023
A subgroup of T cells called T-regulatory cells (Tregs) regulates the body's immune responses to maintain homeostasis and self-tolerance. Tregs are crucial for preventing illnesses like cancer and autoimmunity. However, contrasting patterns of Treg frequency are observed in different autoimmune diseases.
Suvankar, Halder, Samrat, Chatterjee
openaire   +2 more sources

Timing is everything: regulatory overlap in plant cell death

Trends in Plant Science, 2008
Plant development and defence are intimately connected to programmed cell death (PCD). PCD can occur after environmental cues such as pathogen infection, mechanical damage or abiotic stress. However, PCD also constitutes an essential feature of various aspects of growth and development.
Andrew J, Love, Joel J, Milner, Ari, Sadanandom   +2 more
openaire   +2 more sources

Cell Volume Regulatory Ion Channels in Cell Proliferation and Cell Death

2007
Alterations of cell volume are key events during both cell proliferation and apoptotic cell death. Cell proliferation eventually requires an increase of cell volume, and apoptosis is typically paralleled by cell shrinkage. Alterations of cell volume require the participation of ion transport across the cell membrane, including appropriate activity of ...
LANG, F, FÖLLER M, LANG K, LANG P, RITTER M, VERENINOV A, SZABO', ILDIKO', HUBER SM, GULBINS E.   +8 more
openaire   +3 more sources

The Role of Regulatory Cell Death in Vitiligo

DNA and Cell Biology
Vitiligo is one of the common chronic autoimmune skin diseases in clinic, which is characterized by localized or generalized depigmentation and seriously affects the physical and mental health of patients. At present, the pathogenesis of vitiligo is not clear; mainly, heredity, autoimmunity, oxidative stress, melanocyte (MC) self-destruction, and the ...
Lyu-Ye Liu, Si-Jia He, Zhao Chen, Man Ge, Chun-Yi Lyu, Dandan Gao, Ji-Peng Yu, Meng-Han Cai, Jin-Xiang Yuan, Jun-Ling Zhang   +9 more
openaire   +2 more sources

Regulatory Role of microRNAs in Ischemic Cell Death

2020
Cell death is a biological process that results in old cells dying and being replaced by new ones or maybe a result of pathological disorders, localized injury, or trauma resulting in the death of cells. There are many cell death pathways so far reported in various kinds of literature, and many are continuously being discovered and reported having ...
Rajanikant G. K., Pierre Gressens, Sreekala S. Nampoothiri, Gokul Surendran, Cindy Bokobza   +4 more
openaire   +1 more source

Regulatory dendritic cells modulate immune responses via induction of T‐cell apoptotic death

Microsurgery, 2006
AbstractWe describe a regulatory lymphoid dendritic cell (LDC) population propagated from mouse liver nonparenchymal cells (NPC) in IL‐3 and anti‐CD40 monoclonal antibody that are phenotypically mature, and induce T‐cell hyporesponsiveness by promoting T‐cell apoptotic death, which is partially caspase‐dependent, but is unlikely to be mediated by ...
Xiaoyan, Liang, Zongyou, Chen, John J, Fung, Shiguang, Qian, Lina, Lu   +4 more
openaire   +2 more sources

Defining the regulatory role of programmed cell death 4 in laryngeal squamous cell carcinoma

Biochemistry and Cell Biology, 2018
Programmed cell death 4 (PDCD4) is decreased in many different kinds of malignant tumors. EMT endows tumor cells invasive and metastatic properties. However, few studies have determined the role of PDCD4 in the regulation of EMT in the context of laryngeal carcinoma. We examined the relationship between PDCD4 and EMT-associated proteins E-cadherin and
Yuan-Teng, Xu, Rui-Qing, Chen, Gong-Biao, Lin, Xiu-Ling, Fang, Shu-Juan, Yu, Xiao-Hua, Liang, Rong, Zhang   +6 more
openaire   +2 more sources

Expression of cell death regulatory genes and limited apoptosis induction in avian blastodermal cells

Molecular Reproduction and Development, 1998
Apoptosis is a well-established cellular mechanism for selective cell deletion during development. However, little is known about the expression of an apoptotic pathway and its role in determining the relative sensitivity of the early, pre-gastrula, avian embryo to stress-induced cell death.
D E, Muscarella, M K, Rachlinski, S E, Bloom   +2 more
openaire   +2 more sources