Results 231 to 240 of about 5,375,401 (399)

Distinct regulatory elements of SLC6A14 expression contribute to modification of cystic fibrosis phenotypes. [PDF]

Hum Genet
Esmaeili M, Wang C, Lin F, Panjwani N, Chan A, He G, Keenan K, Avolio J, Harris A, Rommens JM, Strug LJ.   +10 more
europepmc   +1 more source

AthaMap web tools for database-assisted identification of combinatorial cis-regulatory elements and the display of highly conserved transcription factor binding sites in Arabidopsis thaliana [PDF]

, 2005
Nils Ole Steffens, Claudia Galuschka, Martin Schindler, Lorenz Bülow, Reinhard Hehl   +4 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer

, 2008
Minh D. To, Christine E. Wong, Anthony N. Karnezis, Reyno Del Rosario, Roberto Di Lauro, Allan Balmain   +5 more
openalex   +1 more source

Muscle-specific activity of the skeletal troponin I promoter requires interaction between upstream regulatory sequences and elements contained within the first transcribed exon. [PDF]

, 1990
William Nikovits, J H Mar, Charles P. Ordahl   +2 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Motif-based models accurately predict cell type-specific distal regulatory elements. [PDF]

Nat Commun
Cornejo-Páramo P, Zhang X, Louis L, Li Z, Yang Y, Wong ES.   +5 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Epigenetic regulation of crx and nrl binding to regulatory elements in the genomes of human retinal neurons

, 2017
Courtney B. Stout
openalex   +1 more source

Characterization of a novel T lymphocyte protein which binds to a site related to steroid/thyroid hormone receptor response elements in the negative regulatory sequence of the human immunodeficiency virus long terminal repeat

, 1992
Kim Orchard, Georgina Lang, Mary Collins, D.S. Latchman   +3 more
openalex   +2 more sources