Results 231 to 240 of about 5,141,166 (402)
Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex
C. Luo+15 more
semanticscholar +1 more source
Regulatory Implications of Monopolies in the Securities Industry [PDF]
Since the mid-1990s, investors and regulators have benefited from a high degree of competition in the Indian securities industry. Even more than all the policy changes that have taken place, it is technology and competition that have transformed the ...
Varma, Jayanth R.
core
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Unveiling Epigenetic Regulatory Elements Associated with Breast Cancer Development. [PDF]
Jardanowska-Kotuniak M+12 more
europepmc +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Identification of cis-regulatory elements required for larval expression of the Drosophila melanogaster alcohol dehydrogenase gene. [PDF]
Victoria Corbin, Tom Maniatis
openalex +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source
Pituitary Pro-Opiomelanocortin Gene Expression Requires Synergistic Interactions of Several Regulatory Elements [PDF]
Marc Therrien, Jacques Drouin
openalex +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Widespread impact of nucleosome remodelers on transcription at cis-regulatory elements. [PDF]
Patty BJ, Dhungana R, Hainer SJ.
europepmc +1 more source