Results 51 to 60 of about 5,375,401 (399)
Spatial clustering and common regulatory elements correlate with coordinated gene expression [PDF]
, 2019 Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes. In prokaryotic cells, a single-input-module motif with one transcription factor regulating multiple target genes can generate ...
Bai, Fan +6 more
core +3 more sources
CEAS: cis-regulatory element annotation system [PDF]
Nucleic Acids Research, 2006 The recent availability of high-density human genome tiling arrays enables biologists to conduct ChIP-chip experiments to locate the in vivo-binding sites of transcription factors in the human genome and explore the regulatory mechanisms. Once genomic regions enriched by transcription factor ChIP-chip are located, genome-scale downstream analyses are ...
Ji, Xuwo +4 more
openaire +2 more sources
The problem field of design in urban renewal plans [PDF]
Nasleđe, 2016 The chosen planning approaches, the regulatory elements and building rules applied on individual plots have a considerable impact on the character and development of urban space.
Dimitrijević-Marković Svetlana
doaj +1 more source
An atlas of gene regulatory elements in adult mouse cerebrum
Nature, 2020 The mammalian cerebrum performs high-level sensory perception, motor control and cognitive functions through highly specialized cortical and subcortical structures1.
Y. Li +27 more
semanticscholar +1 more source
Regulatory elements of the erythropoietin gene [PDF]
Blood, 1991 Abstract Because the human hepatoma cell line Hep3B produces erythropoietin (Epo) in a regulated fashion, it can be used to investigate the cis- acting regulatory elements of the Epo gene. Comparison of primate and mouse sequences shows strong homology not only in the coding sequence but also within the 5′ flanking region, the first ...
S, Imagawa +3 more
openaire +3 more sources
Molecular Oncology, 2023 Mortality from vmelanoma is associated with metastatic disease, but the mechanisms leading to spreading of the cancer cells remain obscure. Spatial profiling revealed that melanoma is characterized by a high degree of heterogeneity, which is established ...
Veronica Manicardi +10 more
doaj +1 more source
Biology, 2023 Cadherins are cell–cell adhesion molecules, fundamental for cell architecture and polarity. E-cadherin to P-cadherin switch can rescue adherens junctions in epithelial tumours.
Celina São José +7 more
doaj +1 more source
eLife, 2020 In embryonic stem cells (ESCs), a core transcription factor (TF) network establishes the gene expression program necessary for pluripotency. To address how interactions between four key TFs contribute to cis-regulation in mouse ESCs, we assayed two ...
Dana M. King +5 more
semanticscholar +1 more source
Regulatory elements in molecular networks
WIREs Systems Biology and Medicine, 2017 Regulatory elements determine the connectivity of molecular networks and mediate a variety of regulatory processes ranging from DNA looping to transcriptional, posttranscriptional, and posttranslational regulation. This review highlights our current understanding of the different types of regulatory elements found in molecular networks with a focus on ...
Ashley S. Doane, Olivier Elemento
openaire +3 more sources
Frontiers in Plant Science, 2023 Plants have evolved various mechanisms to adapt to adverse environmental stresses, such as the modulation of gene expression. Expression of stress-responsive genes is controlled by specific regulators, including transcription factors (TFs), that bind to ...
Dajo Smet +6 more
doaj +1 more source