Results 81 to 90 of about 5,375,401 (399)
Nature Communications, 2019 The majority of common variants associated with common diseases, as well as an unknown proportion of causal mutations for rare diseases, fall in noncoding regions of the genome.
Martin Kircher +8 more
semanticscholar +1 more source
uORFs: Important Cis-Regulatory Elements in Plants
International Journal of Molecular Sciences, 2020 Gene expression is regulated at many levels, including mRNA transcription, translation, and post-translational modification. Compared with transcriptional regulation, mRNA translational control is a more critical step in gene expression and allows for ...
Ting Zhang, Anqi Wu, Yaping Yue, Yu Zhao
semanticscholar +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li +9 more
wiley +1 more source
Presenting a Meta-Heuristic Algorithm to Detect Regulatory Elements in the Genome of Breast Cancer Patients [PDF]
Journal of Advanced Biomedical Sciences, 2020 Background & Objective: Nowadays, in medical sciences, the amount of data on symptoms of people affected with various illnesses on one hand, and finding assistive techniques for the diagnosis of those diseases on the other, has been widespread ...
mohammadjavad hosseinpoor +4 more
doaj
Modular arrangement of regulatory RNA elements [PDF]
RNA Biology, 2017 Due to their simple architecture and control mechanism, regulatory RNA modules are attractive building blocks in synthetic biology. This is especially true for riboswitches, which are natural ligand-binding regulators of gene expression. The discovery of various tandem riboswitches inspired the design of combined RNA modules with activities not yet ...
Roßmanith, Johanna, Narberhaus, Franz
openaire +2 more sources
Evidence of widespread degradation of gene control regions in hominid genomes [PDF]
, 2005 Although sequences containing regulatory elements located close to protein-coding genes are often only weakly conserved during evolution, comparisons of rodent genomes have implied that these sequences are subject to some selective constraints ...
Eyre-Walker, Adam +2 more
core +3 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou +10 more
wiley +1 more source
A Systems Biology Approach on the Regulatory Footprint of Human Endogenous Retroviruses (HERVs)
Diseases, 2022 Human endogenous retroviruses (HERVs) are a family of endogenous retroviruses that comprise the ~8.93% of the human genome sequence, with a high proportion being human specific.
Georgios S. Markopoulos
doaj +1 more source
Identification of candidate regulatory sequences in mammalian 3' UTRs by statistical analysis of oligonucleotide distributions [PDF]
, 2007 3' untranslated regions (3' UTRs) contain binding sites for many regulatory elements, and in particular for microRNAs (miRNAs). The importance of miRNA-mediated post-transcriptional regulation has become increasingly clear in the last few years.
Caselle, Michele +3 more
core +4 more sources
Nature Communications, 2019 Modern genetic studies indicate that human brain evolution is driven primarily by changes in gene regulation, which requires understanding the biological function of largely non-coding gene regulatory elements, many of which act in tissue specific manner.
H. Won +4 more
semanticscholar +1 more source