Results 111 to 120 of about 1,862,836 (297)

Discrete time piecewise affine models of genetic regulatory networks [PDF]

open access: yes, 2005
We introduce simple models of genetic regulatory networks and we proceed to the mathematical analysis of their dynamics. The models are discrete time dynamical systems generated by piecewise affine contracting mappings whose variables represent gene ...
A. Meyroneinc   +4 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Regulatory Fit and Regulatory Mode Fit in Marketing Research:

open access: yesMaketingu Janaru
This study identifies current research trends and proposes future directions through a systematic review of the marketing literature on regulatory fit theory from 2015 to 2025.
Hisaaki Watanabe, Ryota Suga
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Quantifying the Benefits of Trade Facilitation in ASEAN [PDF]

open access: yes
This paper assesses the performance and progress of the ASEAN economies in trade facilitation, and the effect of improved trade facilitation on the regionfs manufacturing trade with a focus on port efficiency, customs environment, regulatory environment ...
Tsunehiro Otsuki
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Validating the Parenting Regulatory Focus Scale

open access: yesPsychological Test Adaptation and Development
: Understanding the motivations and value systems behind parenting behaviors is critical for advancing family science and supporting effective, culturally sensitive interventions.
Xiang Zhou, Richard M. Lee
doaj   +1 more source

Prevent2Protect Project: Regulatory Focus Differences in Sexual Health Knowledge and Practices. [PDF]

open access: yesArch Sex Behav, 2023
Rodrigues DL   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy