Results 131 to 140 of about 1,862,836 (297)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The role of product cues and regulatory focus in the consumers' response to green products: The mediation effects of green attitudes. [PDF]

Front Psychol, 2022
Wang X, Gu Y, Xin H, Qiu P, Wang J.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Regulatory focus and deliberate ignorance: When perceived accessibility leads to the decision to ignore information

International Journal of Studies in Psychology
While extensive research has focused on information seeking, the phenomenon of deliberate ignorance, where individuals choose not to know available information despite negligible acquisition costs and potentially high benefits, remains less understood ...
Raymond Godwin, Agnes Sianipar, Bagus Takwin   +2 more
doaj   +1 more source

Relationship and Sexual Quality in the Wake of COVID-19: Effects of Individual Regulatory Focus and Shared Concerns over the Pandemic. [PDF]

Eur J Investig Health Psychol Educ, 2023
Rodrigues DL, Balzarini RN.
europepmc   +1 more source

Cable Television, New Technologies and the First Amendment After Turner Broadcasting System, Inc. v. F.C.C. [PDF]

, 1995
From the moment it emerged as an independently viable communications medium, the cable television industry has been forced to operate within the shadow of regulatory oversight.
Ugland, Erik
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Innovating agricultural marketing: credit codes as a new tool to boost sales of place-of-origin products

Frontiers in Sustainable Food Systems
IntroductionMerchants often use the place-of-origin as a promotional tool for regionally distinctive agricultural products, yet consumers face challenges verifying origin authenticity. Prior research has centered on detection technologies to build trust,
Hengshu Wei, Guilong Li, Xv Liang, Yuwei Li, Qiuli Huang   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Sustaining eSports Industry and Regulatory Focus: Empirical Evidence From Chinese Universities. [PDF]

Front Psychol, 2022
Zhao G, Cheng Y, Liu X, Meng W.
europepmc   +1 more source