Results 11 to 20 of about 590,520 (267)
Reconstructing regulatory network transitions [PDF]
Trends in Cell Biology, 2011 Cellular responses often involve a transition of cells from one state to another. A transition from a stem cell to a differentiated cell state, for example, might occur in response to gene expression changes induced by a transcription factor, or to signaling cascades triggered by a hormone or pathogen.
Jalean J, Petricka, Philip N, Benfey
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International Journal of Molecular Sciences, 2023 The central role of RNA molecules in cell biology has been an expanding subject of study since the proposal of the “RNA world” hypothesis 60 years ago [...]
Francisco J. Enguita +2 more
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Gene-centered regulatory networks [PDF]
Briefings in Functional Genomics, 2009 Differential gene expression plays a critical role in the development and physiology of multicellular organisms. At a 'systems level' (e.g. at the level of a tissue, organ or whole organism), this process can be studied using gene regulatory network (GRN) models that capture physical and regulatory interactions between genes and their regulators.
Arda, H. Efsun, Walhout, Albertha J M
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Frontiers in Pharmacology, 2022 Essential oil of Coreopsis tinctoria (EOC) is a essential substance extracted from Coreopsis tinctoria with the excellent anti-oxidant effect. However, it is still unclear whether EOC can improve learning and memory impairment and its mechanism.
Yan Qu +10 more
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Frontiers in Pharmacology, 2022 The aging process of human beings is accompanied by the decline of learning and memory ability and progressive decline of brain function, which induces Alzheimer’s Disease (AD) in serious cases and seriously affects the quality of patient’s life.
Yingxue Guo +10 more
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Constructing transcriptional regulatory networks [PDF]
Genes & Development, 2005 Biological networks are the representation of multiple interactions within a cell, a global view intended to help understand how relationships between molecules dictate cellular behavior. Recent advances in molecular and computational biology have made possible the study of intricate transcriptional regulatory networks that describe gene expression as ...
Alexandre, Blais, Brian David, Dynlacht
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The Annals of Applied Statistics, 2010 Published in at http://dx.doi.org/10.1214/10-AOAS350 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
James, Gareth M. +3 more
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Prostate cancer regulatory networks [PDF]
Journal of Cellular Biochemistry, 2009 AbstractAlthough the timing with which common epithelial malignancies arise and become established remains a matter of debate, it is clear that by the time they are detected these tumors harbor hundreds of deregulated, aberrantly expressed or mutated genes.
Altieri, Dario C. +7 more
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The SOS Regulatory Network [PDF]
EcoSal Plus, 2008 All organisms possess a diverse set of genetic programs that are used to alter cellular physiology in response to environmental cues. The gram-negative bacterium Escherichia coli induces a gene regulatory network known as the “SOS response” following exposure to DNA damage, replication fork arrest, and a myriad of ...
Lyle A, Simmons +3 more
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Renal Failure, 2022 Objective We performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy and safety of leflunomide combined with corticosteroids, compared with corticosteroids alone, for IgA nephropathy.Materials and methods Studies were ...
Guangxin Lv, Chengyuan Ming
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