Results 31 to 40 of about 6,140,187 (206)

Impacts of Climate Change on Inequities in Child Health

Children, 2014
This paper addresses an often overlooked aspect of climate change impacts on child health: the amplification of existing child health inequities by climate change.
Charmian M. Bennett, Sharon Friel
doaj   +1 more source

Prognostic Ability of Enhancer RNAs in Metastasis of Non-Small Cell Lung Cancer

Molecules, 2022
(1) Background: Non-small cell lung cancer (NSCLC) is the most common lung cancer. Enhancer RNA (eRNA) has potential utility in the diagnosis, prognosis and treatment of cancer, but the role of eRNAs in NSCLC metastasis is not clear; (2) Methods ...
Jun Liu, Jingyi Jia, Siqiao Wang, Junfang Zhang, Shuyuan Xian, Zixuan Zheng, Lin Deng, Yonghong Feng, Yuan Zhang, Jie Zhang   +9 more
doaj   +1 more source

The Mechanism of Action of Stigmasterol in Bone Formation in Osteoporosis

Current Issues in Molecular Biology
Osteoporosis (OP) is a metabolic bone disease characterized by reduced bone mass and impaired bone microarchitecture, significantly impacting patients’ quality of life.
Cailian Lu, Hong Li, Zhengbo Liu, Sirui Lü, Junxing Liu   +4 more
doaj   +1 more source

RNA Regulatory Networks 2.0

International Journal of Molecular Sciences, 2023
The central role of RNA molecules in cell biology has been an expanding subject of study since the proposal of the “RNA world” hypothesis 60 years ago [...]
Francisco J. Enguita, Ana Lúcia Leitão, John S. Mattick   +2 more
openaire   +3 more sources

BRD4 promotes gouty arthritis through MDM2-mediated PPARγ degradation and pyroptosis

Molecular Medicine
Background Gouty arthritis (GA) is characterized by monosodium urate (MSU) crystal accumulation that instigates NLRP3-mediated pyroptosis; however, the underlying regulatory mechanisms have yet to be fully elucidated.
Xiaoxia Xu, Hongbin Qiu
doaj   +1 more source

Association Between Toe Walking and Repetitive Behaviors in Children with Autism Spectrum Disorder: A Cross-Sectional Phenotypic Analysis

Medicina
Background and Objectives: Toe walking (TW) is frequently observed in children with Autism Spectrum Disorder (ASD), yet its clinical significance remains incompletely understood.
Martina Gnazzo, Giuditta Bargiacchi, Beatrice Gallai, Giulia Spoto, Gabriella Di Rosa, Valentina Baldini, Lucia Parisi, Agata Maltese, Michele Roccella, Eva Germanò, Maria Esposito, Marco Carotenuto   +11 more
doaj   +1 more source

The Regulatory Network of Pseudomonas aeruginosa [PDF]

Microbial Informatics and Experimentation, 2011
Abstract Background Pseudomonas aeruginosa is an important bacterial model due to its metabolic and pathogenic abilities, which allow it to interact and colonize a wide range of hosts, including plants and animals.
Galán-Vásquez, Edgardo, Luna, Beatriz, Martínez-antonio, Agustino   +2 more
openaire   +2 more sources

A multipronged approach to the regulation of workplace bullying [PDF]

, 2013
This paper reviews the substantial body of research on workplace bullying with a view to developing a regulatory framework for controlling and preventing bullying problems.
Braithwaite, Valerie, Australian National University. Regulatory Institutions Network   +1 more
core  

Irreversibility in bacterial regulatory networks

Science Advances
Irreversibility, in which a transient perturbation leaves a system in a new state, is an emergent property in systems of interacting entities. This property has well-established implications in statistical physics but remains underexplored in biological networks, especially for bacteria and other prokaryotes whose regulation of gene ...
Yi Zhao, Thomas P. Wytock, Kimberly A. Reynolds, Adilson E. Motter   +3 more
openaire   +3 more sources

MicroRNA-34a negatively regulates Netrin1 and mediates MEK/ERK pathway to regulate chemosensitivity of gastric cancer cells

Discover Oncology
Objective To explore the mechanism of action of MicroRNAs-34a (miR-34a) and Eurite growth guiding factor 1 (Netrin1) in cisplatin resistance in gastric cancer (GC), providing new clues for overcoming tumor resistance and optimizing anti-tumor therapy for
Haiping Liu, Limin Wang
doaj   +1 more source