Results 21 to 30 of about 590,520 (267)

Single Cell Pluripotency Regulatory Networks [PDF]

PROTEOMICS, 2016
AbstractEmbryonic stem (ES) cells represent a popular model system for investigating development, tissue regeneration and repair. Although much is known about the molecular mechanisms that regulate the balance between self-renewal and lineage commitment in ES cells, the spatiotemporal integration of responsive signalling pathways with core ...
Stumpf, Patrick, Ewing, Rob, Macarthur, Ben D.   +2 more
openaire   +4 more sources

Estimating Sample-Specific Regulatory Networks [PDF]

SSRN Electronic Journal, 2018
Biological systems are driven by intricate interactions among the complex array of molecules that comprise the cell. Many methods have been developed to reconstruct network models of those interactions. These methods often draw on large numbers of samples with measured gene expression profiles to infer connections between genes (or gene products).
Kuijjer, Marieke Lydia, Tung, Matthew George, Yuan, GuoCheng, Quackenbush, John, Glass, Kimberly   +4 more
openaire   +7 more sources

Mitochondria-Targeted Fluorescent Nanoparticles with Large Stokes Shift for Long-Term BioImaging

Molecules, 2023
Mitochondria (MITO) play a significant role in various physiological processes and are a key organelle associated with different human diseases including cancer, diabetes mellitus, atherosclerosis, Alzheimer’s disease, etc.
Xiao Li, Tao Zhang, Xuebo Diao, Li Yu, Yue Su, Jiapei Yang, Zibo Shang, Shuai Liu, Jia Zhou, Guolin Li, Huirong Chi   +10 more
doaj   +1 more source

Biomarker discovery studies for patient stratification using machine learning analysis of omics data: a scoping review

BMJ Open, 2021
Objective To review biomarker discovery studies using omics data for patient stratification which led to clinically validated FDA-cleared tests or laboratory developed tests, in order to identify common characteristics and derive recommendations for ...
Rita Banzi, Jacques Demotes, Paula Garcia, Enrico Glaab, Armin Rauschenberger, Chiara Gerardi   +5 more
doaj   +1 more source

Identification of Key Genes Regulated by Lactylation Modification and Associated with Tumor Immune Microenvironment in Breast Cancer

Current Issues in Molecular Biology
Breast cancer (BRCA) is the most common cancer worldwide, with an incidence exceeding that of lung cancer. Protein lactylation, a newly identified post-translational modification involving the binding of lactic acid to lysine residues, plays an important
Yaohong Xie, Yi Ge, Na Miao, Pengxia Zhang, Jiaqi Xia   +4 more
doaj   +1 more source

Absolute quantification of DNA damage response proteins

Genes and Environment, 2023
Background DNA damage response (DDR) and repair are vital for safeguarding genetic information and ensuring the survival and accurate transmission of genetic material.
Shun Matsuda, Tsuyoshi Ikura, Tomonari Matsuda   +2 more
doaj   +1 more source

Analysis of the radiated electric field strength from in‐house G.fast2 data carrying wire‐line telecommunication network

IET Science, Measurement & Technology, 2021
G.fast profile 212a technology is the perfect choice for an operator offering a broadband service, as it operates using the existing copper telecommunications infrastructure (cables) already installed in user premises.
Josip Milanovic, Domagoj Budisa
doaj   +1 more source

Prognostic Ability of Enhancer RNAs in Metastasis of Non-Small Cell Lung Cancer

Molecules, 2022
(1) Background: Non-small cell lung cancer (NSCLC) is the most common lung cancer. Enhancer RNA (eRNA) has potential utility in the diagnosis, prognosis and treatment of cancer, but the role of eRNAs in NSCLC metastasis is not clear; (2) Methods ...
Jun Liu, Jingyi Jia, Siqiao Wang, Junfang Zhang, Shuyuan Xian, Zixuan Zheng, Lin Deng, Yonghong Feng, Yuan Zhang, Jie Zhang   +9 more
doaj   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

Impacts of Climate Change on Inequities in Child Health

Children, 2014
This paper addresses an often overlooked aspect of climate change impacts on child health: the amplification of existing child health inequities by climate change.
Charmian M. Bennett, Sharon Friel
doaj   +1 more source