Results 21 to 30 of about 7,752,988 (327)

Toward widespread use of virtual trials in medical imaging innovation and regulatory science. [PDF]

Med Phys
The rapid advancement in the field of medical imaging presents a challenge in keeping up to date with the necessary objective evaluations and optimizations for safe and effective use in clinical settings.
Abadi E, Barufaldi B, Lago M, Badal A, Mello-Thoms C, Bottenus N, Wangerin KA, Goldburgh M, Tarbox L, Beaucage-Gauvreau E, Frangi AF, Maidment A, Kinahan PE, Bosmans H, Samei E.   +14 more
europepmc   +2 more sources

Emerging technologies and their impact on regulatory science. [PDF]

Exp Biol Med (Maywood), 2022
There is an evolution and increasing need for the utilization of emerging cellular, molecular and in silico technologies and novel approaches for safety assessment of food, drugs, and personal care products.
Anklam E, Bahl MI, Ball R, Beger RD, Cohen J, Fitzpatrick S, Girard P, Halamoda-Kenzaoui B, Hinton D, Hirose A, Hoeveler A, Honma M, Hugas M, Ishida S, Kass GE, Kojima H, Krefting I, Liachenko S, Liu Y, Masters S, Marx U, McCarthy T, Mercer T, Patri A, Pelaez C, Pirmohamed M, Platz S, Ribeiro AJ, Ribeiro AJ, Rodricks JV, Rusyn I, Salek RM, Schoonjans R, Silva P, Svendsen CN, Sumner S, Sung K, Tagle D, Tong L, Tong W, Eijnden-van-Raaij JVD, Vary N, Wang T, Waterton J, Wang M, Wen H, Wishart D, Yuan Y, Slikker W.   +48 more
europepmc   +2 more sources

Adaptability of AI for safety evaluation in regulatory science: A case study of drug-induced liver injury. [PDF]

Front Artif Intell, 2022
Artificial intelligence (AI) has played a crucial role in advancing biomedical sciences but has yet to have the impact it merits in regulatory science. As the field advances, in silico and in vitro approaches have been evaluated as alternatives to animal
Connor S, Li T, Roberts R, Thakkar S, Liu Z, Tong W.   +5 more
europepmc   +2 more sources

Measurement and Mitigation of Bias in Artificial Intelligence: A Narrative Literature Review for Regulatory Science

Clinical pharmacology and therapy, 2023
Artificial intelligence (AI) is increasingly being used in decision making across various industries, including the public health arena. Bias in any decision‐making process can significantly skew outcomes, and AI systems have been shown to exhibit biases
Magnus Gray, Ravi K Samala, Qi Liu, Denny Skiles, Joshua Xu, Weida Tong, Leihong Wu   +6 more
semanticscholar   +1 more source

ToxAIcology - The evolving role of artificial intelligence in advancing toxicology and modernizing regulatory science.

ALTEX, 2023
Toxicology has undergone a transformation from an observational science to a data-rich discipline ripe for artificial intelligence (AI) integration. The exponential growth in computing power coupled with accumulation of large toxicological datasets has ...
Thomas Hartung
semanticscholar   +1 more source

Nanomedicine and regulatory science: the challenges in Africa

Frontiers in Biomaterials Science, 2023
The integrated approach in the development of nanotechnology is allowing its introduction into multiple fields, including pharmaceutical research, in which there are now several medicines containing nanomaterials or at least making nano-based claims.
N. Z. Nyazema, J. T. Chanyandura, P. O. Kumar   +2 more
semanticscholar   +1 more source

(Bio)manufactured Solutions for Treatment of Bone Defects with Emphasis on US-FDA Regulatory Science Perspective.

Advanced NanoBiomed Research, 2022
Bone defects, with second highest demand for surgeries around the globe, may lead to serious health issues and negatively influence patient lives.
Pejman Ghelich, Mehdi Kazemzadeh-Narbat, Alireza Hassani Najafabadi, M. Samandari, A. Memić, A. Tamayol   +5 more
semanticscholar   +1 more source

The impact of interactive advertising on consumer engagement, recall, and understanding: A scoping systematic review for informing regulatory science

PLoS ONE, 2022
We conducted a scoping systematic review with respect to how consumer engagement with interactive advertising is evaluated and if interactive features influence consumer recall, awareness, or comprehension of product claims and risk disclosures for ...
Kristen Giombi, C. Viator, J. Hoover, Janice P. Tzeng, Helen W. Sullivan, Amie C O'Donoghue, Brian G. Southwell, Leila C. Kahwati   +7 more
semanticscholar   +1 more source

Environmental Fate and Dissipation of Applied dsRNA in Soil, Aquatic Systems, and Plants

Frontiers in Plant Science, 2020
Two primary use patterns exist for dsRNA-based products for crop protection: in planta produced dsRNA such as in a genetically engineered (GE) crop; and topically applied dsRNA such as a spray application.
Pamela Bachman, Pamela Bachman, Joshua Fischer, Zihong Song, Ewa Urbanczyk-Wochniak, Greg Watson   +5 more
doaj   +1 more source

Sequence–Activity Relationships for the Snf7 Insecticidal dsRNA in Chrysomelidae

Frontiers in Plant Science, 2020
The responsiveness of insects to oral delivery of insecticidal dsRNA has been shown to be dependent on dsRNA length and sequence match. Previous work with the western corn rootworm (WCR, Diabrotica virgifera virgifera; Coleoptera: Chrysomelidae ...
Pamela Bachman, Pamela Bachman, Jennifer Fridley, Geoffrey Mueller, William Moar, Steven L. Levine   +5 more
doaj   +1 more source