Results 201 to 210 of about 1,518,123 (337)

Identification of Gallbladder-Specific Distal Regulatory Sequence of Murine Sox17. [PDF]

Genes Cells
Zeng S, Yanagida A, Ota N, Uemura M, Hirate Y, Hiramatsu R, Mizuno N, Kanai Y, Kanai-Azuma M.   +8 more
europepmc   +1 more source

OA repository for regulatory sequence annotations

, 2007
Elodie Portales-Casamar and seven co-authors, PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation, <em> GenomeBiology </em> , October 4, 2007.
openaire   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

An endogenous retroviral element co-opts an upstream regulatory sequence to achieve somatic expression and mobility. [PDF]

Nucleic Acids Res
Rubanova N, Singh D, Barolle L, Chalvet F, Netter S, Poidevin M, Servant N, Bardin AJ, Siudeja K.   +8 more
europepmc   +1 more source

Comparative Analysis Identifies Exonic Splicing Regulatory Sequences—The Complex Definition of Enhancers and Silencers [PDF]

, 2006
Amir Goren, Oren Ram, Maayan Amit, Hadas Keren, Galit Lev-Maor, Ida Vig, Tal Pupko, Gil Ast   +7 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Regulatory sequence-based discovery of anti-defense genes in archaeal viruses. [PDF]

Nat Commun
Bhoobalan-Chitty Y, Xu S, Martinez-Alvarez L, Karamycheva S, Makarova KS, Koonin EV, Peng X.   +6 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Semi-supervised learning with pseudo-labeling compares favorably with large language models for regulatory sequence prediction. [PDF]

Brief Bioinform
Phan H, Brouard C, Mourad R.
europepmc   +1 more source

Regulatory sequence analysis of semaphorin 4D 5' non-coding region. [PDF]

J Cancer, 2019
Qiu L, Jiang H, Luo J, Xi J, Wang X, Pan Y, Chen J, Zhao Y, Sun Q.   +8 more
europepmc   +1 more source