Results 41 to 50 of about 1,518,123 (337)

Analysis of CcDREB1D promoter region from drought-tolerant and susceptible clones of Coffea canephora by homologous genetic transformation of Coffea arabica [PDF]

, 2013
In several plant species, the DREB genes play a key role in responses to abiotic stress. Since the development of molecular markers is one of the major goals for accelerating breeding programs, a study was done to evaluate the sequence variability of the
Alves, Gabriel Sergio Costa, Dechamp, Eveline, Freire, Luciana Pereira, Paiva, L.V., This, Dominique, Andrade, Alan Carvalho, Etienne, Hervé, Marraccini, Pierre   +7 more
core   +1 more source

Localized motif discovery in gene regulatory sequences [PDF]

Bioinformatics, 2010
Abstract Motivation: Discovery of nucleotide motifs that are localized with respect to a certain biological landmark is important in several appli-cations, such as in regulatory sequences flanking the transcription start site, in the neighborhood of known transcription factor binding sites, and in transcription factor binding regions ...
Narang, V., Mittal, A., Sung, W.-K.
openaire   +2 more sources

Predicting gene regulatory regions with a convolutional neural network for processing double-strand genome sequence information.

PLoS ONE, 2020
With advances in sequencing technology, a vast amount of genomic sequence information has become available. However, annotating biological functions particularly of non-protein-coding regions in genome sequences without experiments is still a challenging
Koh Onimaru, Osamu Nishimura, Shigehiro Kuraku   +2 more
doaj   +1 more source

Identification of the regulatory logic controlling Salmonella pathoadaptation by the SsrA-SsrB two-component system. [PDF]

PLoS Genetics, 2010
Sequence data from the past decade has laid bare the significance of horizontal gene transfer in creating genetic diversity in the bacterial world. Regulatory evolution, in which non-coding DNA is mutated to create new regulatory nodes, also contributes ...
Ana M Tomljenovic-Berube, David T Mulder, Matthew D Whiteside, Fiona S L Brinkman, Brian K Coombes   +4 more
doaj   +1 more source

Predicting transcriptional responses to heat and drought stress from genomic features using a machine learning approach in rice

Frontiers in Plant Science, 2023
Plants have evolved various mechanisms to adapt to adverse environmental stresses, such as the modulation of gene expression. Expression of stress-responsive genes is controlled by specific regulators, including transcription factors (TFs), that bind to ...
Dajo Smet, Dajo Smet, Helder Opdebeeck, Helder Opdebeeck, Klaas Vandepoele, Klaas Vandepoele, Klaas Vandepoele   +6 more
doaj   +1 more source

A multiple-instance scoring method to predict tissue-specific cis-regulatory motifs and regions [PDF]

, 2009
Transcription is the central process of gene regulation. In higher eukaryotes, the transcription of a gene is usually regulated by multiple cis-regulatory regions (CRRs).
Jin Gu
core   +2 more sources

Discovering sequences with potential regulatory characteristics

Genomics, 2009
We developed a computational model to explore the hypothesis that regulatory instructions are context dependent and conveyed through specific 'codes' in human genomic DNA. We provide examples of correlation of computational predictions to reported mapped DNase I hypersensitive segments in the HOXA locus in human chromosome 7.
Bina, Minou, Wyss, Phillip, Lazarus, Sheryl A., Shah, Syed R., Ren, Wenhui, Szpankowski, Wojciech, Crawford, Gregory E., Park, Sang P., Song, Xiaohui C.   +8 more
openaire   +2 more sources

Systematic discovery of structural elements governing stability of mammalian messenger RNAs. [PDF]

, 2012
Decoding post-transcriptional regulatory programs in RNA is a critical step towards the larger goal of developing predictive dynamical models of cellular behaviour.
Cristea, Ileana M, Fish, Lisa, Goodarzi, Hani, Greco, Todd M, Najafabadi, Hamed S, Oikonomou, Panos, Salavati, Reza, Tavazoie, Saeed   +7 more
core   +2 more sources

Conservation of the separase regulatory domain

Biology Direct, 2018
ᅟ We report a protein sequence analysis of the cell cycle regulatory protease, separase. The sequence and structural conservation of the C-terminal protease domain has long been recognized, whereas the N-terminal regulatory domain of separase was ...
Michael Melesse, Joshua N. Bembenek, Igor B. Zhulin   +2 more
doaj   +1 more source

The bacterial promoter spacer modulates promoter strength and timing by length, TG-motifs and DNA supercoiling sensitivity

Scientific Reports, 2021
Transcription, the first step to gene expression, is a central coordination process in all living matter. Besides a plethora of regulatory mechanisms, the promoter architecture sets the foundation of expression strength, timing and the potential for ...
Carlo A. Klein, Marc Teufel, Carl J. Weile, Patrick Sobetzko   +3 more
doaj   +1 more source