Results 191 to 200 of about 2,996,073 (354)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Galectin-3 exacerbates autoimmune diabetes by limiting regulatory T cell differentiation and function. [PDF]

Sci Adv
Xie L, Zhang R, Zou H, Hu J, Deng J, Ding J, Liu L, Lin Q, Zhao B, Xu A, Zhou Z, Xiao Y.   +11 more
europepmc   +1 more source

FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

Cell, 2006
Yongqing Wu, M. Borde, V. Heissmeyer, M. Feuerer, A. Lapan, J. Stroud, D. Bates, Liang Guo, A. Han, S. Ziegler, D. Mathis, C. Benoist, Lin Chen, A. Rao   +13 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Nonclinical regulatory considerations for investigational new drug applications for regulatory T cell therapies. [PDF]

Front Med (Lausanne)
Dinh PU, Mihalcik L.
europepmc   +1 more source

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

Nature, 2010
Ye Zheng, Steven Z. Josefowicz, A. Chaudhry, Xiao P. Peng, K. Forbush, A. Rudensky   +5 more
semanticscholar   +1 more source

Suppression of HIV-specific T cell activity by lymph node CD25⁺regulatory T cells from HIV-infected individuals

, 2007
Audrey Kinter, Jonathan P. McNally, Lindsey Riggin, Robert W. Jackson, Gregg Roby, Anthony S. Fauci   +5 more
openalex   +1 more source

regulatory T cell

Citation: 'regulatory T cell' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13644 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests
openaire   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Regulatory T Cell in Kidney Transplant: The Future of Cell Therapy? [PDF]

Antibodies (Basel)
Matarneh A, Patel M, Parikh K, Karasinski A, Kaur G, Shah V, Ghahramani N, Trivedi N.   +7 more
europepmc   +1 more source