Results 241 to 250 of about 1,257,811 (269)

Regulatory T Cells in Obesity

2015
The current concept of the pathogenesis of obesity relates to the inflammation caused by excess of adipose tissue. Regulatory T cells accumulated in visceral adipose tissue (VAT-resident Tregs) are also involved in this pathogenesis. In the present paper the mechanisms responsible for alterations in the number and function of VAT-resident Tregs T in ...
Anna M, Kucharska, Beata, Pyrżak, Urszula, Demkow   +2 more
openaire   +2 more sources

The life of regulatory T cells

Annals of the New York Academy of Sciences, 2013
Foxp3+ regulatory T (Treg) cells are essential for maintaining self‐tolerance and preventing autoimmune reactions. Treg cells arise as a consequence of self‐antigen recognition during the maturation of cells in the thymus, and also following self‐antigen recognition in the periphery.
Iris K, Gratz, Michael D, Rosenblum, Abul K, Abbas   +2 more
openaire   +2 more sources

Regulatory T cells and cancer

Current Opinion in Immunology, 2007
Increasing evidence indicates that T regulatory (Treg) cells have the potent ability to suppress host immune responses, thus preventing autoimmune diseases. However, recent studies demonstrate that tumor cells can recruit these Treg cells to inhibit antitumor immunity in the tumor microenvironment, thus limiting the efficiency of cancer immunotherapy ...
Helen Y, Wang, Rong-Fu, Wang
openaire   +2 more sources

Regulatory T-Cells and Autoimmunity

Journal of Surgical Research, 2006
Approximately 20% of the population is affected by autoimmune or inflammatory diseases mediated by an abnormal immune response. A characteristic feature of autoimmune disease is the selective targeting of a single cell type, organ or tissue by certain populations of autoreactive T-cells.
Niamh, Ni Choileain, H P, Redmond
openaire   +2 more sources

Regulatory T Cells and the Eye

2007
Immune-mediated inflammation can be tolerated in many organs, however in the eye it has devastating consequences, as many of the tissues in the visual axis have limited or no capacity for regeneration. Multiple mechanisms and anatomical adaptations limit the expression of immune-mediated inflammation in the eye.
openaire   +2 more sources

Regulatory T Cells in Psoriasis

2006
Psoriasis is a chronic autoimmune disease in which T lymphocytes are thought to be central in the pathogenesis. Recently, a T cell subset population was identified, whose role is to suppress inflammatory responses triggered by T effector cells. T cells in this new population are referred to as T regulatory cells. We studied their number and activity in
M H, Kagen, T S, McCormick, K D, Cooper
openaire   +2 more sources

A cis-regulatory atlas in maize at single-cell resolution

Cell, 2021
Alexandre P Marand, Zongliang Chen, Andrea Gallavotti   +2 more
exaly  

Regulatory T Cells in the Galt

1987
The discussion about the importance of regulatory T cells for the differentiation of B cell precursors into IgA producing cells is controversial. Whereas the antigen driven differentiation of precursor cells is the central point of the B cell centered theories (1), others have suggested a crucial influence of T cells for the end stage differentiation ...
openaire   +2 more sources

Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer

Cancer Cell, 2022
Huocong Huang, Zhaoning Wang, Yuqing Zhang   +2 more
exaly  

Gene regulatory network inference in the era of single-cell multi-omics

Nature Reviews Genetics, 2023
Pau Badia-I-Mompel, Lorna Wessels, Sophia Müller-Dott   +2 more
exaly