Results 251 to 260 of about 2,996,073 (354)

Liver-specific paraoxonase-1 alleviates regulatory T cell-driven immunosuppression via metabolic reprogramming in hepatocellular carcinoma. [PDF]

Nat Commun
Lu Z, Shi H, Gao R, Zhong C, Zhang W, Zhu J, Huang J, Liu R, Xing Y, Chu Y, Sun H, Shi G, Ke A, Zhou J, Cai J, Fan J, Gao P, Huang C.   +17 more
europepmc   +1 more source

Impact of alemtuzumab treatment on the survival and function of human regulatory T cells in vitro

, 2013
Evis Havari, Michael J. Turner, Juanita Campos‐Rivera, Srinivas Shankara, Tri‐Hung Nguyen, Bruce Roberts, William Siders, Johanne Kaplan   +7 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Correction: REV-ERB regulates RORγt+ regulatory T cell specification and function through the Bhlhe40-c-Maf axis. [PDF]

J Exp Med
Hu X, Liu Z, Li Y, You Y, Yue K, Liang Y, Loo CS, Yu J, Leblanc M, Wang D, Li H, Zheng Y.   +11 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Genistein enhances anti-PD-1 efficacy in melanoma by suppressing regulatory T cell differentiation and activity. [PDF]

Sci Rep
Mo F, Hong M, Chen X, Wang Q, Dong C.
europepmc   +1 more source

REVIEW ARTICLE: Th1/Th2/Th17 and Regulatory T‐Cell Paradigm in Pregnancy

American Journal of Reproductive Immunology, 2010
S. Saito, A. Nakashima, T. Shima, Mika Ito   +3 more
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Circulating Naïve Regulatory T Cell Subset Displaying Increased STAT5 Phosphorylation During Controlled Ovarian Hyperstimulation Is Associated with Clinical Pregnancy and Progesterone Levels. [PDF]

Int J Mol Sci
Rakić K, Goropevšek A, Kozar N, Kovačič B, Čurič S, Zakelšek A, Homšak E, Reljič M.   +7 more
europepmc   +1 more source

IL-35-mediated induction of a potent regulatory T cell population

Nature Immunology, 2010
L. Collison, Vandana Chaturvedi, Abigail L. Henderson, P. Giacomin, C. Guy, Jaishree Bankoti, D. Finkelstein, K. Forbes, C. Workman, Scott A. Brown, J. Rehg, Michael L. Jones, H. Ni, D. Artis, M. Turk, D. Vignali   +15 more
semanticscholar   +1 more source