Results 311 to 320 of about 2,996,073 (354)
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The Cancer Journal, 2010
Regulatory T cells inhibit cellular immunity and represent an obstacle for the development of cancer immunotherapy. The understanding of Treg cellular biology has exponentially increased during the last 10 years, driven primarily by elegant in vivo studies of mouse models systems and in vitro studies of human cells.
Tatiana N, Golovina +1 more
openaire +2 more sources
Regulatory T cells inhibit cellular immunity and represent an obstacle for the development of cancer immunotherapy. The understanding of Treg cellular biology has exponentially increased during the last 10 years, driven primarily by elegant in vivo studies of mouse models systems and in vitro studies of human cells.
Tatiana N, Golovina +1 more
openaire +2 more sources
T regulatory cells turn on T regulatory cells
Blood, 2009In this issue of Blood , Miao and colleagues demonstrate that Tregs from a FoxP3 transgenic mouse injected with a normally immunogenic FVIII plasmid not only suppress the response to FVIII but also may “turn on” host Tregs upon adoptive transfer.
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Seminars in Immunopathology, 2016
Our initial understanding of immune-regulatory cells was based on the discovery of suppressor cells that assure peripheral T-cell tolerance and promote immune homeostasis. Research has particularly focused on the importance of regulatory T cells (Tregs) for immune modulation, e.g.
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Our initial understanding of immune-regulatory cells was based on the discovery of suppressor cells that assure peripheral T-cell tolerance and promote immune homeostasis. Research has particularly focused on the importance of regulatory T cells (Tregs) for immune modulation, e.g.
openaire +3 more sources
2016
Regulatory T cells (Tregs) are CD4+ T cells that inhibit autoreactive effector T cells to suppress antitumor immunity. Many anticancer therapeutics have limited efficacy, and it is thought that Tregs may, in part, be one of the reasons. From this viewpoint, Tregs may be a therapeutic target for cancer immunotherapy.
M. Monteiro +4 more
openaire +2 more sources
Regulatory T cells (Tregs) are CD4+ T cells that inhibit autoreactive effector T cells to suppress antitumor immunity. Many anticancer therapeutics have limited efficacy, and it is thought that Tregs may, in part, be one of the reasons. From this viewpoint, Tregs may be a therapeutic target for cancer immunotherapy.
M. Monteiro +4 more
openaire +2 more sources
2018
The tumor microenvironment consists of numerous and diverse immune cells many of which act to suppress the immune system response against cancer cells. Regulatory T cells (Tregs) perform a key role in mediating this immunosuppressive response via a variety of mechanisms.
Vaia Florou, Breelyn A. Wilky
openaire +1 more source
The tumor microenvironment consists of numerous and diverse immune cells many of which act to suppress the immune system response against cancer cells. Regulatory T cells (Tregs) perform a key role in mediating this immunosuppressive response via a variety of mechanisms.
Vaia Florou, Breelyn A. Wilky
openaire +1 more source
CTLA-4 Control over Foxp3+ Regulatory T Cell Function
Science, 2008K. Wing +7 more
semanticscholar +1 more source
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
Nature, 2007L. Collison +9 more
semanticscholar +1 more source
Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
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