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A Novel Cyclopropenyl Fatty Acid Library Reveals Tissue-Specific Preferences for Regulatory T Cell Uptake Through Click-Chemistry

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Heieis G   +14 more
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Thymic regulatory T cells

Autoimmunity Reviews, 2005
Several types of T regulatory (Treg) cells have been described in both mice and humans, including natural or professional (CD4+CD25+ T cells) and adaptive (Th3 and Tr1 cells) Treg cells. The former develops in the thymus and results in an endogeneous long-lived population of self-antigen-specific T cells in the periphery poised to prevent potentially ...
MAGGI, ENRICO   +5 more
openaire   +4 more sources

T regulatory cells in xenotransplantation

Xenotransplantation, 2009
Abstract:  The role of T regulatory cells (Treg) in the induction and maintenance of allograft tolerance is being studied to a great extent. In contrast, little is known on their potential to prevent graft rejection in the field of xenotransplantation, where acute vascular rejection mediated by cellular and humoral mechanisms and thrombotic ...
Muller, Yannick   +5 more
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Regulatory T Cells in Psoriasis [PDF]

open access: possible, 2006
Psoriasis is a chronic autoimmune disease in which T lymphocytes are thought to be central in the pathogenesis. Recently, a T cell subset population was identified, whose role is to suppress inflammatory responses triggered by T effector cells. T cells in this new population are referred to as T regulatory cells. We studied their number and activity in
Thomas S. McCormick   +2 more
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T regulatory cells turn on T regulatory cells

Blood, 2009
In this issue of Blood , Miao and colleagues demonstrate that Tregs from a FoxP3 transgenic mouse injected with a normally immunogenic FVIII plasmid not only suppress the response to FVIII but also may “turn on” host Tregs upon adoptive transfer.
openaire   +3 more sources

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