Results 211 to 220 of about 1,958,413 (325)

Metabolic regulation of regulatory T cells: mechanisms, heterogeneity, and implications in disease. [PDF]

Front Immunol
Getachew F, Hu J, Benamar M.
europepmc   +1 more source

Impact of alemtuzumab treatment on the survival and function of human regulatory T cells in vitro

, 2013
Evis Havari, Michael J. Turner, Juanita Campos‐Rivera, Srinivas Shankara, Tri‐Hung Nguyen, Bruce Roberts, William Siders, Johanne Kaplan   +7 more
openalex   +1 more source

FOXP3 Identifies Regulatory CD25^brightCD4⁺ T Cells in Rheumatic Joints [PDF]

, 2006
Duojia Cao, Ola Börjesson, P. Larsson, Anna Rudin, Iva Gunnarsson, Lars Klareskog, Vivianne Malmström, Christina Trollmo   +7 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

CD318 expression defines a novel subset of human CD8⁺ regulatory T cells. [PDF]

Sci Adv
Do JS, Chen WK, Hung YW, Arribas-Layton D, Lu C, Gu A, Montero E, Carmo AM, Reijonen H.   +8 more
europepmc   +1 more source

Regulatory T cells promote corneal endothelial cell survival following transplantation via interleukin-10 [PDF]

, 2019
Giulia Coco, William Foulsham, Takeshi Nakao, Jia Yin, Afsaneh Amouzegar, Y. Taketani, Sunil K. Chauhan, Reza Dana   +7 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Table S8 from CD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer

Stéphane Fattori, Aude Le Roy, Jemila Houacine, Lucie Robert, Riad Abès, Laurent Gorvel, Samuel Granjeaud, Marie-Sarah Rouviére, Amira Ben Amara, Nicolas Boucherit, Carole Tarpin, Jihane Pakradouni, Emmanuelle Charafe‐Jauffret, Gilles Houvenaeghel, Éric Lambaudie, François Bertucci, Philippe Rochigneux, Anthony Gonçalvès, Arnaud Foussat, Anne-Sophie Chrétien, Daniel Olive   +20 more
openalex   +1 more source

Regulatory T cells and regulatory NK cells play essential roles for maintenance of pregnancy

, 2012
Shigeru Saito, Tomoko Shima, Akitoshi Nakashima   +2 more
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source