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Regulatory T cells and asthma

Clinical & Experimental Allergy, 2009
AbstractAirway inflammation in asthma is characterized by activation of T helper type‐2 (Th2) T cells, IgE production and eosinophilia. In many cases, this process is related to an inappropriate T cell response to environmental allergens, and other T cell‐dependent pathways may also be involved (such as Th17).
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CD147 in regulatory T cells

Cellular Immunology, 2013
CD147 or EMMPRIN belongs to the immunoglobulin superfamily of membrane receptors and is expressed in epithelial cells, cancer cells and T cells of the immune system. In T cells CD147 functions as a receptor for soluble cyclophilins and is involved in chemotaxis.
Johannes, Landskron, Kjetil, Taskén
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Regulatory T cells in Arthritis

2015
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases and is characterized by inflammation and subsequent bone destruction in multiple joints. In mice, depletion of regulatory T (Treg) cells results in the onset of a variety of autoimmune diseases including arthritis, while replenishment of Treg cells alleviates arthritic symptoms ...
Noriko, Komatsu, Hiroshi, Takayanagi
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The life of regulatory T cells

Annals of the New York Academy of Sciences, 2013
Foxp3+ regulatory T (Treg) cells are essential for maintaining self‐tolerance and preventing autoimmune reactions. Treg cells arise as a consequence of self‐antigen recognition during the maturation of cells in the thymus, and also following self‐antigen recognition in the periphery.
Iris K, Gratz   +2 more
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Regulatory T Cells in Obesity

2015
The current concept of the pathogenesis of obesity relates to the inflammation caused by excess of adipose tissue. Regulatory T cells accumulated in visceral adipose tissue (VAT-resident Tregs) are also involved in this pathogenesis. In the present paper the mechanisms responsible for alterations in the number and function of VAT-resident Tregs T in ...
Anna Małgorzata Kucharska   +2 more
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Regulatory T Cells in the Galt

1987
The discussion about the importance of regulatory T cells for the differentiation of B cell precursors into IgA producing cells is controversial. Whereas the antigen driven differentiation of precursor cells is the central point of the B cell centered theories (1), others have suggested a crucial influence of T cells for the end stage differentiation ...
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Regulatory T Cells and the Eye

2007
Immune-mediated inflammation can be tolerated in many organs, however in the eye it has devastating consequences, as many of the tissues in the visual axis have limited or no capacity for regeneration. Multiple mechanisms and anatomical adaptations limit the expression of immune-mediated inflammation in the eye.
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Regulatory T Cells in Psoriasis

2006
Psoriasis is a chronic autoimmune disease in which T lymphocytes are thought to be central in the pathogenesis. Recently, a T cell subset population was identified, whose role is to suppress inflammatory responses triggered by T effector cells. T cells in this new population are referred to as T regulatory cells. We studied their number and activity in
M H, Kagen, T S, McCormick, K D, Cooper
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Regulatory T Cells and Human Disease

Annual Review of Immunology, 2020
Norihisa Mikami   +2 more
exaly  

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

Nature, 2021
Brett Morrison   +2 more
exaly  

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