Results 241 to 250 of about 1,927,651 (292)

Neonatal Thymic Dynamics Influence Autoimmune Pathology by Shaping the Suppressive Potential of Regulatory T Cells. [PDF]

open access: yesAm J Pathol
Matsuzawa S   +6 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Regulatory T cells in homeostasis and disease: molecular mechanisms and therapeutic potential. [PDF]

open access: yesSignal Transduct Target Ther
Wang L   +8 more
europepmc   +1 more source

Immunomodulation of UVB-induced regulatory T cells prevents the establishment of squamous cell carcinoma. [PDF]

open access: yesJ Immunother Cancer
Anwaar S   +5 more
europepmc   +1 more source

TRIP13 promotes the expansion and immunosuppression of CD4+Foxp3+ regulatory T cells by sustaining HAT1 stability. [PDF]

open access: yesCell Death Dis
He T   +13 more
europepmc   +1 more source

Rapamycin-modified novel tolerogenic dendritic cells induce liver graft tolerance through MHC-II+CD8+ regulatory T cells. [PDF]

open access: yesHepatol Commun
Zhou L   +11 more
europepmc   +1 more source

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