Results 41 to 50 of about 1,139,425 (157)
Plasticity of human CD4 T cell subsets
Frontiers in Immunology, 2014 Human beings are exposed to a variety of different pathogens, which induce tailored immune responses and consequently generate highly diverse populations of pathogen-specific T cells.
Jens eGeginat +8 more
doaj +1 more source
Circulation Research, 2006 See related article, pages 1109–1116 Myocarditis is an acute inflammatory disease of the heart and a precursor of dilated cardiomyopathy.1–8 Dilated cardiomyopathy is a more chronic disease which is characterized by ventricular hypertrophy and which may be a direct result of myocarditis and lead to heart failure.1–3,9 Myocarditis is often ...
openaire +1 more source
Emerging Functions of Regulatory T Cells in Tissue Homeostasis
Frontiers in Immunology, 2018 CD4+Foxp3+ regulatory T-cells (Tregs) are a unique subset of helper T-cells, which regulate immune response and establish peripheral tolerance. Tregs not only maintain the tone and tenor of an immune response by dominant tolerance but, in recent years ...
Amit Sharma +3 more
doaj +1 more source
Tr1-like T cells- an enigmatic regulatory T cell lineage
Frontiers in Immunology, 2016 The immune system evolved to respond to foreign invaders and prevent autoimmunity to self-antigens. Several types of regulatory T cells facilitate the latter process.
Anna Malgorzata White +2 more
doaj +1 more source
Dual Mechanisms for Balancing Th17 and Treg Cell Fate by CREB
EBioMedicine, 2017 Th17 cells, which express the cytokine IL-17A, and master regulator RORγt, are important in the inflammatory response to fungal and bacterial pathogens, but also have a pathogenic role in many inflammatory disorders. In contrast, regulatory T cells (Treg)
Antony Symons, Wenjun Ouyang
doaj +1 more source
Multiple subsets of regulatory T-cells
Бюллетень сибирской медицины, 2020 Regulatory T-lymphocytes play a central role in the immunological tolerance system. To date, existence of many different subpopulations of regulatory T-cells have been described.
S. V. Kupriyanov +2 more
doaj +1 more source
Unexpected Help: Follicular Regulatory T Cells in the Germinal Center
Frontiers in Immunology, 2018 Follicular helper T (Tfh) cells are necessary for germinal center (GC) formation and within the GC, provide key signals to B cells for their differentiation into plasmablasts and plasma cells that secrete high-affinity and isotype-switched antibody (Ab).
Markus M. Xie, Alexander L. Dent
doaj +1 more source
MCSF drives regulatory DC development in stromal co-cultures supporting hematopoiesis
BMC Immunology, 2018 Background Splenic stroma overlaid with hematopoietic progenitors supports in vitro hematopoiesis with production of dendritic-like cells. Co-cultures of murine lineage-depleted bone marrow over the 5G3 stromal line produce two populations of cells ...
Sawang Petvises +2 more
doaj +1 more source
Frontiers in Immunology, 2019 Control and elimination of blood-stage Plasmodium chabaudi AS infection requires CD4+ Th1 cells that secrete IFN-γ and T follicular help (Tfh) cells together with B cell production of antibody.
Floriana Berretta +6 more
doaj +1 more source
Regulatory T Cells in Transplantation
Transplantation Proceedings, 2011 T Regulatory cells (Treg) play an important role in the induction and maintenance of immunological tolerance to self and alloantigens. Recent findings in experimental transplant models have demonstrated that Treg can control acute and delayed allograft rejection.
openaire +6 more sources