Results 41 to 50 of about 304,002 (266)
Understanding how T helper cells learn to coordinate effective immune responses through the lens of reinforcement learning [PDF]
Phys. Rev. Research 3, 013222 (2021), 2019 The adaptive immune system of vertebrates can detect, respond to, and memorize diverse pathogens from past experience. While the clonal selection of T helper (Th) cells is the simple and established mechanism to better recognize new pathogens, the question that still remains unexplored is how the Th cells can acquire better ways to bias the responses ...
arxiv +1 more source
Distilling regulatory T cell inducers [PDF]
Nature Reviews Immunology, 2013 Treatment with a mixture of 17 Clostridia strains or with short-chain fatty acids promotes colonic TRegcell function.
openaire +2 more sources
More Than Effects in Skin: Ultraviolet Radiation-Induced Changes in Immune Cells in Human Blood
Frontiers in Immunology, 2021 Cells of the skin and circulation are in constant two-way communication. Following exposure of humans to sunlight or to phototherapy, there are alterations in the number, phenotype and function of circulating blood cells.
Prue H. Hart, Mary Norval
doaj +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Cholera-Like Enterotoxins and Regulatory T cells
Toxins, 2010 Cholera toxin (CT) and the heat-labile enterotoxin of E. coli (LT), as well as their non toxic mutants, are potent mucosal adjuvants of immunization eliciting mucosal and systemic responses against unrelated co-administered antigens in experimental ...
Evelyne Kohli +5 more
doaj +1 more source
Using MRI Cell Tracking to Monitor Immune Cell Recruitment in Response to a Peptide-Based Cancer Vaccine [PDF]
, 2017 Purpose: MRI cell tracking can be used to monitor immune cells involved in the immunotherapy response, providing insight into the mechanism of action, temporal progression of tumour growth and individual potency of therapies. To evaluate whether MRI could be used to track immune cell populations in response to immunotherapy, CD8+ cytotoxic T cells ...
arxiv +1 more source
Stochastic effects in autoimmune dynamics [PDF]
Frontiers in Physiology 9, 45 (2018), 2018 Among various possible causes of autoimmune disease, an important role is played by infections that can result in a breakdown of immune tolerance, primarily through the mechanism of "molecular mimicry". In this paper we propose and analyse a stochastic model of immune response to a viral infection and subsequent autoimmunity, with account for the ...
arxiv +1 more source
Regulatory T Cells in Transplantation
Transplantation Proceedings, 2011 T Regulatory cells (Treg) play an important role in the induction and maintenance of immunological tolerance to self and alloantigens. Recent findings in experimental transplant models have demonstrated that Treg can control acute and delayed allograft rejection.
openaire +7 more sources
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source