Results 21 to 30 of about 14,721,754 (256)

T regulatory cells in cord blood--FOXP3 demethylation as reliable quantitative marker [PDF]

, 2010
Regulatory T-cells (Tregs), characterized as CD4+CD25(hi) T-cells expressing FOXP3, play a crucial role in controlling healthy immune development during early immune maturation. Recently, FOXP3 demethylation was suggested to be a novel marker for natural
Laura Layland, Liu, Jing, Jing Liu, Schaub, Bianca, Layland, Laura, Mutius, Erika von, Illi, Sabina, Lluis, Anna, Bianca Schaub, Erika von Mutius, Anna Lluis, Sabina Illi, Olek, Sven, Sven Olek, Liu, J;Lluis, A;Illi, S;Layland, L;Olek, S;von Mutius, E;Schaub, B   +14 more
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Regulatory immune cells in transplantation. [PDF]

, 2012
Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control both the innate immune response triggered by the injured ...
Bushell, Andrew, Wood, Kathryn, Bushell, A, Hester, J, Wood, Kathryn J, Andrew Bushell, Joanna Hester, Kathryn J. Wood, Wood, KJ, Hester, Joanna   +9 more
core   +1 more source

Regulatory T-Cell Phenotyping Using CyTOF

, 2023
Regulatory T cells are an important component of the immune system that plays a key role in maintaining homeostasis. Identification of distinct regulatory T cell subsets is essential to understand their function.
Sjögren, Florence,, Magnusson, Louise,, Casas, Rosaura,, Barcenilla, Hugo,, Pihl, Mikael,   +4 more
core   +1 more source

Regulatory T cells

Current Opinion in Pharmacology, 2004
Regulatory T (TR) cells are a subset of T cells that function to control immune responses. Different populations of TR cells have been described, including thymically derived CD4(+)CD25+ TR cells and Tr1 cells induced in the periphery through exposure to antigen.
Thompson, C, Powrie, F
openaire   +3 more sources

Rapamycin and abundant TCR stimulation are required for the generation of stable human induced regulatory T cells

Clinical & Translational Immunology, 2020
Objectives Regulatory T cells (Tregs) are a vital sub‐population of CD4+ T cells with major roles in immune tolerance and homeostasis. Given such properties, the use of regulatory T cells for immunotherapies has been extensively investigated, with a ...
Juewan Kim, Christopher M Hope, Griffith B Perkins, Sebastian O Stead, Jacqueline C Scaffidi, Francis D Kette, Robert P Carroll, Simon C Barry, Patrick Toby Coates   +8 more
doaj   +1 more source

Freeze-thaw lysates of Plasmodium falciparum-infected red blood cells induce differentiation of functionally competent regulatory T cells from memory T cells. [PDF]

, 2012
In addition to naturally occurring regulatory T (nTreg) cells derived from the thymus, functionally competent Treg cells can be induced in vitro from peripheral blood lymphocytes in response to TCR stimulation with cytokine costimulation.
Finney, Olivia C, Riley, Eleanor M, Finney, OC, Lawrence, Emma, Gray, Alice P, Njie, Madi, Walther, M, Walther, Michael, Riley, EM, Gray, AP, Lawrence, E, Njie, M   +11 more
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In vitro Regulatory T cells Differentiation From Naïve T Cells

Bio-Protocol, 2014
In the past years, a subset of regulatory T cells (Tregs) expressing CD4, CD25 and the transcription factor FoxP3 has gained considerable attention as key regulators of T-cell tolerance and homeostasis (Sakaguchi, 2004).
Tomas Dalotto , Gabriel Rabinovich, Marian Salatino   +2 more
doaj   +1 more source

MicroRNA 10a marks regulatory T cells. [PDF]

PLoS ONE, 2012
MicroRNAs (miRNAs) are crucial for regulatory T cell (Treg) stability and function. We report that microRNA-10a (miR-10a) is expressed in Tregs but not in other T cells including individual thymocyte subsets.
Lukas T Jeker, Xuyu Zhou, Kseniya Gershberg, Dimitri de Kouchkovsky, Malika M Morar, Gustavo Stadthagen, Anders H Lund, Jeffrey A Bluestone   +7 more
doaj   +1 more source

Regulatory T cells in retroviral infections. [PDF]

PLoS Pathogens, 2018
Tight regulation of immune responses is not only critical for preventing autoimmune diseases but also for preventing immunopathological damage during infections in which overactive immune responses may be more harmful for the host than the pathogen ...
Kim J Hasenkrug, Claire A Chougnet, Ulf Dittmer   +2 more
doaj   +1 more source

Regulatory T Cells in Autoimmune Vasculitis

Frontiers in Immunology, 2022
Blood vessels are indispensable for host survival and are protected from inappropriate inflammation by immune privilege. This protection is lost in patients with autoimmune vasculitides, a heterogeneous group of diseases causing damage to arteries ...
Ke Jin, Simon Parreau, Kenneth J. Warrington, Matthew J. Koster, Gerald J. Berry, Jörg J. Goronzy, Jörg J. Goronzy, Cornelia M. Weyand, Cornelia M. Weyand   +8 more
doaj   +1 more source