Results 21 to 30 of about 1,245,074 (217)
Clinical & Translational Immunology, 2020 Objectives Regulatory T cells (Tregs) are a vital sub‐population of CD4+ T cells with major roles in immune tolerance and homeostasis. Given such properties, the use of regulatory T cells for immunotherapies has been extensively investigated, with a ...
Juewan Kim +8 more
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Regulatory T Cells in GVHD Therapy
Frontiers in Immunology, 2021 Graft versus host disease (GVHD) is a common complication and the leading cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Wen-wen Guo +5 more
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Characteristics of Regulatory T cells
Journal of Medical Science, 2016 Regulatory T cells (Tregs) is heterogenic subpopulation of T cells that is able to suppress function of effector cells during the immune response. Among them are natural (nTreg) and induced Treg (Tr1, Th3, CD4+CD25-).
Magdalena Frydrychowicz +6 more
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MicroRNA 10a marks regulatory T cells. [PDF]
PLoS ONE, 2012 MicroRNAs (miRNAs) are crucial for regulatory T cell (Treg) stability and function. We report that microRNA-10a (miR-10a) is expressed in Tregs but not in other T cells including individual thymocyte subsets.
Lukas T Jeker +7 more
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In vitro Regulatory T cells Differentiation From Naïve T Cells
Bio-Protocol, 2014 In the past years, a subset of regulatory T cells (Tregs) expressing CD4, CD25 and the transcription factor FoxP3 has gained considerable attention as key regulators of T-cell tolerance and homeostasis (Sakaguchi, 2004).
Tomas Dalotto +2 more
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Regulatory T cells in retroviral infections. [PDF]
PLoS Pathogens, 2018 Tight regulation of immune responses is not only critical for preventing autoimmune diseases but also for preventing immunopathological damage during infections in which overactive immune responses may be more harmful for the host than the pathogen ...
Kim J Hasenkrug +2 more
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Regulatory T Cells in Autoimmune Vasculitis
Frontiers in Immunology, 2022 Blood vessels are indispensable for host survival and are protected from inappropriate inflammation by immune privilege. This protection is lost in patients with autoimmune vasculitides, a heterogeneous group of diseases causing damage to arteries ...
Ke Jin +8 more
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Memory regulatory T cells in pregnancy
Frontiers in Immunology, 2023 Pregnancy requires the process of maternal immune tolerance to semi-allogeneic embryos. In contrast, an overreactive maternal immune system to embryo-specific antigens is likely to result in the rejection of embryos while damaging the invading placenta ...
Zeyang Chen +5 more
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Regulatory T cells in paracoccidioidomycosis
Virulence, 2019 This review addresses the role of regulatory T cells (Tregs), which are essential for maintaining peripheral tolerance and controlling pathogen immunity, in the host response against Paracoccidioides brasiliensis, a primary fungal pathogen.
Vera L. G. Calich +2 more
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Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation
Cell Reports, 2018 Summary: Psoriasis is a chronic relapsing, remitting interleukin (IL)-23/IL-17-driven skin disease mediated by the interplay of T cells and polymorphonuclear granulocytes. Although preclinical studies have provided insights into the mechanisms of disease
Tom Hartwig +10 more
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