Results 11 to 20 of about 14,721,754 (256)
Regulatory T cells in paracoccidioidomycosis [PDF]
Virulence, 2019 This review addresses the role of regulatory T cells (Tregs), which are essential for maintaining peripheral tolerance and controlling pathogen immunity, in the host response against Paracoccidioides brasiliensis, a primary fungal pathogen.
Vera L. G. Calich +2 more
doaj +3 more sources
Anti-regulatory T cells are natural regulatory effector T cells [PDF]
Cell Stress, 2019 Niels Ødum
doaj +5 more sources
Journal of Investigative Dermatology, 2006 Immunologic self-tolerance is critically dependent on the induction but also on the downregulation of immune responses. Though ignored and neglected for many years, suppressor T cells, now renamed regulatory T cells (Tregs), play an important role in the negative regulation of immune responses. Several subsets of Tregs have been described.
Beissert, Stefan +2 more
openaire +2 more sources
Freeze-thaw lysates of P. falciparum-infected red blood cells induce differentiation of functionally competent regulatory T cells from memory T cells. [PDF]
, 2012 : In addition to naturally occurring regulatory T (nTreg) cells derived from the thymus, functionally competent Treg cells can be induced in vitro from peripheral blood lymphocytes in response to T-cell receptor stimulation with cytokine co-stimulation ...
Finney, OC +5 more
core +3 more sources
Tissue regulatory T cells [PDF]
Immunology, 2020 SummaryFoxp3+ CD4+ regulatory T cells (Tregs) are an immune cell lineage endowed with immunosuppressive functionality in a wide array of contexts, including both anti‐pathogenic and anti‐self responses. In the past decades, our understanding of the functional diversity of circulating or lymphoid Tregs has grown exponentially.
Prudence PokWai Lui +2 more
openaire +2 more sources
Regulating regulatory T cells [PDF]
Bone Marrow Transplantation, 2006 Regulatory T cells (Tregs) are a specialized subpopulation of T cells that act to suppress activation of other immune cells and thereby maintain immune system homeostasis, self-tolerance as well as control excessive response to foreign antigens. The mere concept of Tregs was the subject of significant controversy among immunologists for many years ...
N T, Le, N, Chao
openaire +2 more sources
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF alpha therapy [PDF]
, 2004 Regulatory T cells have been clearly implicated in the control of disease in murine models of autoimmunity. The paucity of data regarding the role of these lymphocytes in human autoimmune disease has prompted us to examine their function in patients with
Jamie G. Evans +13 more
core +1 more source
Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with Hepatitis B virus infection [PDF]
, 2005 CD4+ CD25+ regulatory T cells have been shown to maintain peripheral tolerance against self and foreign antigens. In this study we analyzed the effect of circulating CD4+ CD25+ T cells on CD8+-T-cell responses of patients with chronic and resolved ...
Gotto, J +19 more
core +1 more source
Current Biology, 2005 First discovered… The existence of T regulatory cells was first suggested by several animal models in the 1970s. Organ-specific autoimmunity was found to be induced in specific strains of mice that had been thymectomized 3 days after birth but not after thymectomy at 0 or 7 days.
openaire +2 more sources