Results 11 to 20 of about 1,927,651 (292)
Journal of Investigative Dermatology, 2006 Immunologic self-tolerance is critically dependent on the induction but also on the downregulation of immune responses. Though ignored and neglected for many years, suppressor T cells, now renamed regulatory T cells (Tregs), play an important role in the
Beissert, Stefan +2 more
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Regulatory T cells as immunotherapy [PDF]
Frontiers in Immunology, 2014 Regulatory T cells (Tregs) suppress exuberant immune system activation and promote immunologic tolerance. Because Tregs modulate both innate and adaptive immunity, the biomedical community has developed intense interest in using Tregs for immunotherapy.
Benjamin David Singer +2 more
doaj +3 more sources
Regulatory immune cells in transplantation [PDF]
Nature Reviews Immunology, 2012 Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control the innate immune response triggered by the injured ...
Bushell, Andrew +2 more
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Anti-regulatory T cells are natural regulatory effector T cells [PDF]
Cell Stress, 2019 Niels Ødum
doaj +5 more sources
Tissue regulatory T cells [PDF]
Immunology, 2020 SummaryFoxp3+ CD4+ regulatory T cells (Tregs) are an immune cell lineage endowed with immunosuppressive functionality in a wide array of contexts, including both anti‐pathogenic and anti‐self responses. In the past decades, our understanding of the functional diversity of circulating or lymphoid Tregs has grown exponentially.
Prudence PokWai Lui +2 more
openaire +2 more sources
Regulating regulatory T cells [PDF]
Bone Marrow Transplantation, 2006 Regulatory T cells (Tregs) are a specialized subpopulation of T cells that act to suppress activation of other immune cells and thereby maintain immune system homeostasis, self-tolerance as well as control excessive response to foreign antigens. The mere concept of Tregs was the subject of significant controversy among immunologists for many years ...
N T, Le, N, Chao
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Regulatory T cells and cardiovascular diseases
Chinese Medical Journal, 2023 . Inflammation is a major underlying mechanism in the progression of numerous cardiovascular diseases (CVDs). Regulatory T cells (Tregs) are typical immune regulatory cells with recognized immunosuppressive properties.
Wangling Hu +4 more
doaj +1 more source
Regulatory T cells induced by B cells: a novel subpopulation of regulatory T cells
Journal of Biomedical Science, 2017 Regulatory T cells play a crucial role in the homeostasis of the immune response. In addition to CD4+Foxp3+ regulatory T cells, several subsets of Foxp3- regulatory T cells, such as T helper 3 (Th3) cells and type 1 regulatory T (Tr1) cells, have been ...
Chien-Hui Chien, Bor-Luen Chiang
doaj +1 more source
TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells [PDF]
, 2013 Although diverse functions of different toll-like receptors (TLR) on human natural regulatory T cells have been demonstrated recently, the role of TLR-related signals on human induced regulatory T cells remain elusive.
Gang Qin +10 more
core +5 more sources