Results 211 to 220 of about 305,737 (250)
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T-regulatory lymphocytes and chronic viral hepatitis
Expert Opinion on Biological Therapy, 2007Both hepatitis B virus (HBV) and hepatitis C virus (HCV) can cause persistent viral infection in humans. Chronic infection is associated with a risk of cirrhosis and hepatocellular carcinoma. The cause of chronic infection is unknown. A large body of evidence suggests that a failure of the adaptive immune response is critical in the establishment of ...
Simon M, Rushbrook +2 more
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The Role of Recombinant Glycodelin in the Differentiation of Regulatory T-Lymphocytes
Doklady Biological Sciences, 2022The effect of recombinant glycodelin (GdA) on the number of T-regulatory lymphocytes (Treg) in a culture of activated CD4+ lymphocytes was investigated, while simultaneously assessing the proliferative status of the cells. Recombinant GdA from E. coli and from HEK293 cells were used in the study at concentrations of 0.2; 2 and 10 µg/mL.
K Yu, Shardina +5 more
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Regulatory Role of T Lymphocytes in Atopic Dermatitis
2008Eczema does not occur in the absence of T cells. Here we provide an overview on the regulatory impact which T cells have on the establishment and maintenance of atopic dermatitis. Particularly, we outline the role of different T-helper cell subsets (i.e.
T, Werfel, M, Wittmann
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REGULATORY T-LYMPHOCYTES IN LYMPHOMAGENESIS
2020B-cell lymphomas are a heterogenous group of tumours that account for 85% of all non-Hodgkin lymphomas (NHL), tumours derived from cells of lymphoid lineage. B-lymphomas originate from various developmental stages of B lymphocytes. Classical Hodgkin’s lymphoma (cHL) also originates from B lymphocytes.
Gršković, Paula +5 more
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The role of regulatory t lymphocytes in asthma pathogenesis
Current Allergy and Asthma Reports, 2005Several subtypes of regulatory or suppressive T cells have been described that can prevent activation of effector T cells in vitro and in vivo in animal models. Recent evidence suggests a deficit in suppressive activity of both CD4(+)CD25(+) regulatory T cells, and interleukin (IL)-10 producing regulatory T cells may play a role in development of ...
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Murine CD8+ regulatory T lymphocytes: The new era
Human Immunology, 2008Regulatory T lymphocytes unequivocally play a major role in the maintenance of immunologic homeostasis. The first descriptions of regulatory T lymphocytes concerned CD8(+) cells, but this field was brought into discredit when some of its central tenets turned out to be erroneous. CD4(+) regulatory T cells took over and, with the help of newly developed
Céline, Pomié +2 more
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Development of Thymic Regulatory T Lymphocytes
2019A healthy immune system should maintain a balance between the ability to respond to infectious agents and tumor cells at the same time that sustains self-tolerance. For this purpose, the immune system must be capable of restraining foreign antigens, stopping the immune response after the resolution of a problem and blocking autoreactivity of immune ...
Larissa Vasconcelos-Fontes +4 more
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Regulatory function of human CD4+ cytolytic T lymphocytes
Transplant Immunology, 1999Allograft rejection is mediated by both CD4+ and CD8+ T cells. The lytic function of the classic CD8+ cytolytic T lymphocytes (CTL) occurs through recognition of allogeneic major histocompatibility complex (MHC) class I on the surface of the graft. CD4+ CTL recognize MHC class II through a direct recognition pathway or an indirect pathway where MHC ...
N J, Poindexter +3 more
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Regulatory Lymphocytes in T Cell Functions in Chickens
1977Our contemporary understanding of the immune system involves the concept of two distinct expressions of immunity as well as the division of lymphocyte types into functional subpopulations. Inherent in the development of this complexity is the discernment that some form of control mechanism must have evolved simultaneously.
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Role of α-fetoprotein in differentiation of regulatory T lymphocytes
Doklady Biological Sciences, 2017The effect of native α-fetoprotein (AFP) on the expression of T-regulatory lymphocyte (Treg) markers by activated CD4+ lymphocytes with different proliferative status was studied. α-Fetoprotein did not affect the ratio of proliferating and non-proliferating activated CD4+ cells.
V A, Chereshnev +6 more
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