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Mechanisms of Surveillance of Dendritic Cells by Regulatory T Lymphocytes
2015Regulatory T cells (Tregs) are critical to maintain the homeostasis of the organism, i.e., to prevent (excessive) inflammatory reactions against self and nonself. Data in the literature suggest that a variety of suppressive mechanisms exist that may act selectively depending on the tissue environment. An interesting question is whether dendritic cells (
Maxime, Dhainaut, Muriel, Moser
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Journal of Clinical Oncology, 2011
4632 Background: Tumor-infiltrating lymphocytes are functionally important and correlate with clinical outcome in several tumor entities. In prostate cancer, systematic profiling of the number and subtype of lymphatic cells in the tumor tissue based on large patient cohorts are lacking. Methods: We explored the prognostic significance of the density of
Trepel, Martin +8 more
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4632 Background: Tumor-infiltrating lymphocytes are functionally important and correlate with clinical outcome in several tumor entities. In prostate cancer, systematic profiling of the number and subtype of lymphatic cells in the tumor tissue based on large patient cohorts are lacking. Methods: We explored the prognostic significance of the density of
Trepel, Martin +8 more
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Contingent Genetic Regulatory Events in T Lymphocyte Activation
Science, 1989Interaction of antigen in the proper histocompatibility context with the T lymphocyte antigen receptor leads to an orderly series of events resulting in morphologic change, proliferation, and the acquisition of immunologic function. In most T lymphocytes two signals are required to initiate this process, one supplied by the antigen receptor and the ...
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The Effects of Tacrolimus Ointment on Regulatory T Lymphocytes in Atopic Dermatitis
Journal of Clinical Immunology, 2006Only very recently studies were conducted in order to evaluate the impact of regulatory T (Treg) cells in the pathophysiology of atopic dermatitis (AD). Nine adult patients with moderate-to-severe AD in riacutization period of a chronic disease were given tacrolimus ointment, while seven hydrocortisone butyrate ointment, that served as controls.
Caproni, Marzia +5 more
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Regulatory factors for initial T lymphocyte lineage specification
Current Opinion in Hematology, 2007Initiation of T lymphocyte development depends on balanced regulatory inputs from multiple essential transcription factors. This review highlights contributions of E2A, hematopoietic transcription factor PU.1, growth factor independence (Gfi)-1, T cell factor (TCF)-1, and Runx factors and their interactions with the Notch pathway to promote T cell ...
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Bulletin du cancer, 2008
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and also the third most common cause of cancer-related death. HCC arises most frequently in males with cirrhosis, which is most often a consequence of chronic hepatitis infection (HBV and HCV) or alcohol abuse.
Delhem, N. +6 more
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Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and also the third most common cause of cancer-related death. HCC arises most frequently in males with cirrhosis, which is most often a consequence of chronic hepatitis infection (HBV and HCV) or alcohol abuse.
Delhem, N. +6 more
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RELATIONSHIP BETWEEN MICROVASCULAR T REGULATORY LYMPHOCYTES AND CIRCULATING LYMPHOCYTES
2015Objective: Both innate and adaptive immune systems may contribute to the pathogenesis of cardiovascular disease and vascular remodeling through inflammation and oxidative stress. Particularly, the balance between Th1 effector lymphocytes (producing interferon-[gamma]), Th 17 (producing IL-17) and T regulatory (Treg) lymphocytes, which elicit an anti ...
DE CIUCEIS, Carolina +18 more
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Proceedings of the National Academy of Sciences of the United States of America, 2021
Jae Hun Shin +2 more
exaly
Jae Hun Shin +2 more
exaly
The Regulatory Role of T Lymphocytes in Wound Healing
The Journal of Trauma: Injury, Infection, and Critical Care, 1990A, Barbul, M C, Regan
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