Results 31 to 40 of about 291,895 (251)

B and T Immunoregulation: A New Insight of B Regulatory Lymphocytes in Autism Spectrum Disorder

Frontiers in Neuroscience, 2021
Introduction: Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental disorder characterized by a complex pathogenesis, by impairment social communication and interaction, and may also manifest repetitive patterns of behavior.
Andrea De Giacomo, Concetta Domenica Gargano, Marta Simone, Maria Giuseppina Petruzzelli, Chiara Pedaci, Donatella Giambersio, Lucia Margari, Maddalena Ruggieri   +7 more
doaj   +1 more source

Immunohistochemical evaluation of HLA-G and FoxP3+ T regulatory cells in oral cavity and lower lip squamous cell carcinomas

Brazilian Oral Research, 2019
: Human Leukocyte Antigen G (HLA-G) is a molecule involved in the tumor immunosuppression and also in the generation of regulatory T (Treg) cells, thus leading to evasion to the immune system host, and consequently, contributing to tumor progression in ...
Amanda Katarinny Goes Gonzaga, Hellen Bandeira de Pontes Santos, Janaina Cristiana Oliveira Crispim, Lélia Batista de Souza, Gustavo Martelli Palomino   +4 more
doaj   +1 more source

The role of regulatory T cells in the modulation of anti-tumor immune response [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2013
It has been shown that the loss of regulatory function by deple­ + Regulatory T cells (Treg) represent a subset of CD4 T cells whose function is to suppress immune responses.
Radosavljević Gordana D., Jovanović Ivan P., Kanjevac Tatjana V., Arsenijević Nebojša N.   +3 more
doaj   +1 more source

Regulatory T Cell-Enhancing Therapies to Treat Atherosclerosis

Cells, 2021
Experimental studies have provided strong evidence that chronic inflammation triggered by the sub-endothelial accumulation of cholesterol-rich lipoproteins in arteries is essential in the initiation and progression of atherosclerosis.
Hafid Ait-Oufella, Jean-Rémi Lavillegrand, Alain Tedgui   +2 more
doaj   +1 more source

T regulatory lymphocytes in patients with endometriosis

Molecular Medicine Reports, 2014
The present study aimed to investigate the presence of T regulatory cells (Tregs) in the peripheral blood (PB) and peritoneal fluid (PF) in females with endometriosis. The present study included 42 patients who underwent laparoscopy between 2010 and 2011. Flow cytometry was used to determine the percentage of Tregs in the PF and PB of the patients.
Marek, Gogacz, Izabela, Winkler, Agnieszka, Bojarska-Junak, Jacek, Tabarkiewicz, Andrzej, Semczuk, Tomasz, Rechberger, Aneta, Adamiak   +6 more
openaire   +4 more sources

Human regulatory T cells induce T-lymphocyte senescence [PDF]

Blood, 2012
Abstract Regulatory T (Treg) cells have broad suppressive activity on host immunity, but the fate and function of suppressed responder T cells remains largely unknown. In the present study, we report that human Treg cells can induce senescence in responder naive and effector T cells in vitro and in vivo.
Jian, Ye, Xingxu, Huang, Eddy C, Hsueh, Qunyuan, Zhang, Chunling, Ma, Yanping, Zhang, Mark A, Varvares, Daniel F, Hoft, Guangyong, Peng   +8 more
openaire   +2 more sources

REGULATORY T LYMPHOCYTES

Praxis medica, 2010
<p>Regulatory T cells represent unique CD4+CD25+ population of T lymphocytes, which are involved in many immunological events. These cells have very important role in maintaining peripheral tolerance, prevention of autoimmune diseases, in immunological respond to infection, particularly by intracellular microorganisms as well as in a ...
A. Arsović, I. Radić, S. Savić, B. Ilić, D. Baksić   +4 more
openaire   +1 more source

Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms

Neurobiology of Disease, 2012
Activated microglia and infiltrating lymphocytes are neuropathological hallmarks of amyotrophic lateral sclerosis (ALS), a fatal motoneuron disease.
Weihua Zhao, David R. Beers, Bing Liao, Jenny S. Henkel, Stanley H. Appel   +4 more
doaj   +1 more source

FEATURES OF THE PHENOTYPE OF REGULATORY T CELLS IN EARLY AND ADVANCED RHEUMATOID ARTHRITIS

Научно-практическая ревматология, 2018
Objective: to analyze the levels of CD3+, CD3+CD4+, CD3+CD8+, and CD3-CD56+ T lymphocytes, FoxP3+ regulatory T cells (Treg), and CD19+ B lymphocytes in patients with early and advanced rheumatoid arthritis (RA). Subjects and methods.
A. S. Avdeeva, Yu. P. Rubtsov, T. V. Popkova, D. T. Dyikanov, A. P. Aleksankin, E. L. Nasonov   +5 more
doaj   +1 more source

The Role of Cluster of Differentiation 39 (CD39) and Purinergic Signaling Pathway in Viral Infections

Pathogens, 2023
CD39 is a marker of immune cells such as lymphocytes and monocytes. The CD39/CD73 pathway hydrolyzes ATP into adenosine, which has a potent immunosuppressive effect.
Alaa Elsaghir, Ehsan M. W. El-Sabaa, Abdulrahman K. Ahmed, Sayed F. Abdelwahab, Ibrahim M. Sayed, Mohamed A. El-Mokhtar   +5 more
doaj   +1 more source