Results 21 to 30 of about 172 (99)
CSF/serum ratios: modern approach to assess intrathecal response [PDF]
Инфекция и иммунитетCSF/serum ratios are the quotients of protein concentrations between the cerebrospinal fluid and blood serum. This method provides an objective assessment of proteins amount and origin in the cerebrospinal fluid.
Alexandra M. Deomkina +3 more
doaj +2 more sources
The Usefulness of Two CXCL13 Assays on Cerebrospinal Fluid for the Diagnosis of Lyme Neuroborreliosis: a Retrospective Study in a Routine Clinical Setting. [PDF]
Journal of Clinical Microbiology, 2021 Tamara van Gorkom +2 more
exaly +2 more sources
Intrathecal Kappa Free Light Chains in Relation to IgM Synthesis and MRZH Reaction in a Mixed Neurological Cohort [PDF]
Journal of NeurochemistryDirk Fitzner +1 more
exaly +2 more sources
Journal of Neurochemistry, Volume 159, Issue 3, Page 618-628, November 2021., 2021 We investigated the sensitivity, specificity, and overall diagnostic accuracy of Kappa Free Light Chain (KFLC)‐index in multiple sclerosis (MS). KFLC‐index was prospectively determined as part of the diagnostic workup in patients with suspected MS (n = 327) between May 2013 and February 2020.
Igal Rosenstein +6 more
wiley +1 more source
The role of antibody indexes in clinical virology [PDF]
, 2021 Background: Serological techniques are an essential part of the diagnostic tools used in clinical virology. Among these techniques, antibody indexes are not novel, but do require specific expertise.
Shamier, Marc C. +7 more
core +2 more sources
Arquivos de Neuro-Psiquiatria, 2007 INTRODUCTION: Multiple sclerosis (MS) is a chronic, inflammatory and progressive disease of the central nervous system in which local inflammatory injuries of the brain white matter appears, being the most outstanding feature the myeline loss ...
Bárbara Padilla-Docal +6 more
doaj +1 more source
Intrathecal IgG Synthesis: A Resistant and Valuable Target for Future Multiple Sclerosis Treatments
Multiple Sclerosis International, Volume 2015, Issue 1, 2015., 2015 Intrathecal IgG synthesis is a key biological feature of multiple sclerosis (MS). When acquired early, it persists over time. A growing body of evidence suggests that intrathecal Ig‐secreting cells may be pathogenic either by a direct action of toxic IgG or by locally secreting bystander toxic products. Intrathecal IgG synthesis depends on the presence
Mickael Bonnan, Bianca Weinstock-Guttman
wiley +1 more source
Advances in Geriatrics, Volume 2014, Issue 1, 2014., 2014 The number of people afflicted with Alzheimer’s disease (AD) and other types of dementing conditions has grown exponentially in the last decades. This review focuses on the diagnostic role of the classic cerebrospinal fluid (CSF) biomarkers of neurochemical dementia diagnostics (NDD) and critically discusses potential strategies for the development and
Piotr Lewczuk, Richard C. Dodel
wiley +1 more source
, 2018 Objective: This study aimed to evaluate laboratory oligoclonal band (OCB) patterns together with related IgG results and compare these results with data obtained through final clinical diagnosis.
Karabudak, Rana +6 more
core +1 more source
A sex‐dependent algorithm including kappa free light chain for multiple sclerosis diagnosis
Scandinavian Journal of Immunology, Volume 100, Issue 6, December 2024.K‐index and Q KFLC showed good accuracy in MS diagnosis when studied distinguishing between sexes, similar to OCB. The combined sex‐dependent algorithm including K‐index, Q KFLC and OCB yields the highest diagnostic accuracy in multiple sclerosis diagnosis.
Julia Maroto‐García +8 more
wiley +1 more source