Results 51 to 60 of about 1,160,351 (242)
, 2017 Recent advances in combining deep learning and Reinforcement Learning have shown a promising path for designing new control agents that can learn optimal policies for challenging control tasks.
Givargis, Tony, Mirzaei, Hamid
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Experimental Investigation of Steel Plate Shear Walls under Shear-Compression Interaction
Shock and Vibration, 2019 Four scaled one-storey single-bay steel plate shear wall (SPSW) specimens with unstiffened panels were tested to determine their behaviour under cyclic loadings. The shear walls had moment-resisting beam-to-column connections.
Yang Lv +5 more
doaj +1 more source
IEEE Access, 2023 In this paper, a quality diversity optimization method (QDOM) based on an adaptive bound-searching algorithm and diversity-selecting immune algorithm is proposed for solving bilinear matrix inequality (BMI) problems in control system design. By using the
Shiuan-Yeh Chen +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Effect of water film and paste film thicknesses on printability of 3D printed low cement UHPC
Case Studies in Construction MaterialsTo address the limitations of 3D printed concrete, such as low ductility and susceptibility to cracking, the development of 3D printed low cement ultra-high performance concrete (3DP-LC-UHPC) represents an effective approach.
Ye Shi +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Concrete Gas Permeability: Implications for Hydrogen Storage Applications
Applied SciencesConcrete is widely utilized across various industries as a containment material. One essential property related to its performance is permeability, which determines its ability to allow the passage of gases or liquids through its pores and capillaries ...
Luana Abreu Araujo +7 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source