Results 41 to 50 of about 112,162 (267)

Comfort or hesitancy: A cross-sectional study of modifiable factors associated with co-vaccination behavior among United States and Canadian adults

open access: yesPreventive Medicine Reports
Objective: Co-vaccination, or receiving multiple vaccines at once, may improve vaccination uptake and reduce missed opportunities to vaccinate. Although generally considered safe and effective, co-vaccination is not well accepted outside of travel and ...
Emily Frith   +3 more
doaj   +1 more source

A survey of benchmarks for reinforcement learning algorithms

open access: yesSouth African Computer Journal, 2020
Reinforcement learning has recently experienced increased prominence in the machine learning community. There are many approaches to solving reinforcement learning problems with new techniques developed constantly.
Belinda Stapelberg, Katherine Mary Malan
doaj   +1 more source

What do people really think about the RSV vaccine? Study of unsolicited text replies from adults over 60

open access: yesHumanities & Social Sciences Communications
A digital health intervention (DHI) using SMS precision nudging to drive RSV vaccine uptake among adults over 60 was launched with a large community pharmacy chain in 2023, two months after the vaccine’s FDA approval for adult administration in the ...
E. Susanne Blazek   +5 more
doaj   +1 more source

Reinforcement Learning: Theory and Applications in HEMS

open access: yesEnergies, 2022
The steep rise in reinforcement learning (RL) in various applications in energy as well as the penetration of home automation in recent years are the motivation for this article.
Omar Al-Ani, Sanjoy Das
doaj   +1 more source

Inpatient Exposure, Confidence, and Knowledge in Pediatric Hematology/Oncology: Evaluating General Pediatric Residents During 2025 ACGME Curriculum Change

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background General pediatricians often evaluate hematologic and oncologic presentations before subspecialty consultation, yet the 2025 Accreditation Council for Graduate Medical Education (ACGME) pediatric requirements reduce inpatient pediatric hematology/oncology (PHO) time, raising questions about resident readiness.
Colburn Yu, Rohini Jain
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Parallel model-based and model-free reinforcement learning for card sorting performance

open access: yesScientific Reports, 2020
The Wisconsin Card Sorting Test (WCST) is considered a gold standard for the assessment of cognitive flexibility. On the WCST, repeating a sorting category following negative feedback is typically treated as indicating reduced cognitive flexibility ...
Alexander Steinke   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Risk-Sensitive Reinforcement Learning [PDF]

open access: yesNeural Computation, 2014
We derive a family of risk-sensitive reinforcement learning methods for agents, who face sequential decision-making tasks in uncertain environments. By applying a utility function to the temporal difference (TD) error, nonlinear transformations are effectively applied not only to the received rewards but also to the true transition probabilities of ...
Yun Shen   +3 more
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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