Results 41 to 50 of about 296,024 (311)
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Behavioral SciencesSocial media addiction has become a global public health challenge, and understanding its mechanism’s complexity requires the integration of the transitional characteristics of addiction development stages and breaking through the traditional single ...
Jingsong Wang, Shen Wang
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2013 The development of successful pharmacotherapeutics for the treatment of alcoholism is predicated upon understanding the biological action of alcohol. A limitation of the alcohol research field has been examining the effects of alcohol only and ignoring ...
Gerald A Deehan +4 more
doaj +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Response Speed as a Function of Different Reinforcement Conditions and a Ready Signal [PDF]
, 1967 80 preschool children were each administered 40 trials on a key-pressing apparatus. Marbles served as reinforcers. So given a ready signal performed faster than So not given a ready signal.
Sheikh, Anees A
core +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
The power of associative learning and the ontogeny of optimal behaviour [PDF]
Royal Society Open Science, 2016 Behaving efficiently (optimally or near-optimally) is central to animals' adaptation to their environment. Much evolutionary biology assumes, implicitly or explicitly, that optimal behavioural strategies are genetically inherited, yet the behaviour of ...
Magnus Enquist +2 more
doaj +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Reinforcement and Punishment Shape the Learning Dynamics in fMRI Neurofeedback
Frontiers in Human Neuroscience, 2020 IntroductionNeurofeedback (NF) using real-time functional magnetic resonance imaging (fMRI) has proven to be a valuable neuroscientific tool for probing cognition and promising therapeutic approach for several psychiatric disorders.
Manfred Klöbl +7 more
doaj +1 more source
Asymmetric and adaptive reward coding via normalized reinforcement learning.
PLoS Computational Biology, 2022 Learning is widely modeled in psychology, neuroscience, and computer science by prediction error-guided reinforcement learning (RL) algorithms. While standard RL assumes linear reward functions, reward-related neural activity is a saturating, nonlinear ...
Kenway Louie
doaj +1 more source