Results 31 to 40 of about 20,124 (268)

Fluorescent Light Energy (FLE) Generated through Red LED Light and a Natural Photoconverter Gel as a New, Non-Invasive Approach for Facial Age Control: A Pilot Study

open access: yesCosmetics, 2023
This study, for the first time, evaluated the safety and efficacy of a new natural-based topical gel containing a spirulina extract. This photoconverter gel generates fluorescent light energy (FLE) via a red LED light device, which is proven to be ...
Giuseppe Scarcella   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Shannon Entropy of Gray Matter Eigenmodes: A Novel Biomarker for Alzheimer's Disease and Heterogeneous MCI Trajectories

open access: yesAdvanced Science
Current Alzheimer's disease (AD) diagnostics rely on late‐stage cognitive assessments or invasive biomarkers. Neuroimaging offers non‐invasive alternatives, but single‐modality approaches (structural atrophy or functional connectivity) face limitations ...
Yumeng Li   +5 more
doaj   +1 more source

In Vivo Skin Regeneration and Wound Healing Using Cell Micro-Transplantation

open access: yesPharmaceutics, 2022
Background: The accumulation of senescent cells in tissues alters tissue homeostasis and affects wound healing. It is also considered to be the main contributing factor to aging.
Lucia Nanić   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Old Woman’s Farcical Rejuvenation in The Rejuvenation of Miss Semaphore (1897)

open access: yesCahiers Victoriens et Edouardiens, 2022
Charlotte O’Conor Eccles’s The Rejuvenation of Miss Semaphore (1897) is a comedic New Woman narrative in which a lonely, middle-aged, single woman gets rejuvenated after drinking an elixir.
Somi Ahn
doaj   +1 more source

Rejuvenating Tithonus [PDF]

open access: yesEMBO reports, 2013
Four recent publications, including one in this issue by Surani and colleagues, report that Prdm14 preserves the pluripotent stem cell state by inhibiting FGF signalling and global DNA methylation.
Kyle M, Loh, Bing, Lim
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Planning Optimal Rejuvenation Policy for Aging Software Systems via a Two-Layer Model

open access: yesIEEE Access, 2020
Software rejuvenation is a proactive fault management technique widely used for preventing performance degradation and failures due to software aging.
Jingwei Li   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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