Results 51 to 60 of about 20,249 (219)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Aquifer hydraulic characteristics using D-Z parameters: a case study of Lohaghat block, Champawat district, Uttarakhand, India

Discover Applied Sciences
This study investigates the geoelectrical properties of shallow aquifers and estimates their hydraulic parameters in the Lohaghat block of the Champawat district, Uttarakhand.
Somvir Singh, Nepal C. Mondal
doaj   +1 more source

Elastostatic loading rejuvenation behavior in bulk metallic glasses and its origin: A review

Journal of Materials Research and Technology
Bulk metallic glasses (BMGs) that exhibit superior properties compared to their crystalline counterparts, such as high strength, excellent corrosion resistance and good magnetic properties, are emerging as advanced engineering materials.
Seyyedeh Maryam Mirhashemi, Mehdi Malekan   +1 more
doaj   +1 more source

The 5-Step Filler Hand Rejuvenation: Filling with Hyaluronic Acid

Plastic and Reconstructive Surgery, Global Open, 2019
Many patients are pursuing simultaneous facial and hand rejuvenation with the latter receiving increased interest in recent years. Various materials have been purported to rejuvenate the hands including fat, calcium hydroxyapatite, and hyaluronic fillers.
Nima Khosravani, BS, MS, Lee Weber, BS, Rina Patel, BS, MS, Anup Patel, MD, MBA   +3 more
doaj   +1 more source

LASMIK laser biorevitalization: mechanisms and therapeutic experience

Dermatology Reports, 2020
LASMIK laser biorevitalization is a well-known technology developed in Russia that is based on laser phoresis as a method to enhance percutaneous penetration of substances. The article describes the mechanisms that act here and factors that determine the
Sergey Vladimirovich Moskvin, Aleksandr Agubechirovich Khadartsev   +1 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

In Vitro and In Vivo Assessment of an Innovative Peeling System with Azelaic and Tranexamic Acids for Targeted Hyperpigmentation Reduction

Dermatology and Therapy
Introduction Melanin, derived from tyrosine, plays a pivotal role in skin pigmentation through melanogenesis. Disruptions in this process lead to hyperpigmentation, a condition affecting skin tone and quality of life.
Russell Wong, Mariangela G. de O. Sichmann, James Sun, Alexis R. Kim, Robert J. Bianchini, Kevin D. Hermanson, Louis Chabert   +6 more
doaj   +1 more source

PPARgamma Deficiency Counteracts Thymic Senescence

Frontiers in Immunology, 2017
Thymic senescence contributes to increased incidence of infection, cancer and autoimmunity at senior ages. This process manifests as adipose involution. As with other adipose tissues, thymic adipose involution is also controlled by PPARgamma.
David Ernszt, David Ernszt, Krisztina Banfai, Krisztina Banfai, Zoltan Kellermayer, Attila Pap, Janet M. Lord, Judit E. Pongracz, Judit E. Pongracz, Krisztian Kvell, Krisztian Kvell   +10 more
doaj   +1 more source

Senescence in Mesenchymal Stem Cells: Functional Alterations, Molecular Mechanisms, and Rejuvenation Strategies

Frontiers in Cell and Developmental Biology, 2020
Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and differentiation. There is increasing evidence of the therapeutic value of MSCs in various clinical situations, however, these cells gradually lose their regenerative ...
Jing Liu, Jing Liu, Yue Ding, Zhongmin Liu, Zhongmin Liu, Xiaoting Liang, Xiaoting Liang   +6 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source