Results 61 to 70 of about 20,124 (268)

The 5-Step Filler Hand Rejuvenation: Filling with Hyaluronic Acid

Plastic and Reconstructive Surgery, Global Open, 2019
Many patients are pursuing simultaneous facial and hand rejuvenation with the latter receiving increased interest in recent years. Various materials have been purported to rejuvenate the hands including fat, calcium hydroxyapatite, and hyaluronic fillers.
Nima Khosravani, BS, MS, Lee Weber, BS, Rina Patel, BS, MS, Anup Patel, MD, MBA   +3 more
doaj   +1 more source

LASMIK laser biorevitalization: mechanisms and therapeutic experience

Dermatology Reports, 2020
LASMIK laser biorevitalization is a well-known technology developed in Russia that is based on laser phoresis as a method to enhance percutaneous penetration of substances. The article describes the mechanisms that act here and factors that determine the
Sergey Vladimirovich Moskvin, Aleksandr Agubechirovich Khadartsev   +1 more
doaj   +1 more source

Rejuvenation

Clinical Sciences and Clinical Research
CellSonic has been saving lives for many years by curing chronic disease, something that biochemists cannot do. It is now evident that Cell Sonic’s improvement on lives goes further, it makes people biologically younger. This article examines two cases in detail. The ladies are both 59 years old and live on opposite sides of the world.
openaire   +2 more sources

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

In Vitro and In Vivo Assessment of an Innovative Peeling System with Azelaic and Tranexamic Acids for Targeted Hyperpigmentation Reduction

Dermatology and Therapy
Introduction Melanin, derived from tyrosine, plays a pivotal role in skin pigmentation through melanogenesis. Disruptions in this process lead to hyperpigmentation, a condition affecting skin tone and quality of life.
Russell Wong, Mariangela G. de O. Sichmann, James Sun, Alexis R. Kim, Robert J. Bianchini, Kevin D. Hermanson, Louis Chabert   +6 more
doaj   +1 more source

PPARgamma Deficiency Counteracts Thymic Senescence

Frontiers in Immunology, 2017
Thymic senescence contributes to increased incidence of infection, cancer and autoimmunity at senior ages. This process manifests as adipose involution. As with other adipose tissues, thymic adipose involution is also controlled by PPARgamma.
David Ernszt, David Ernszt, Krisztina Banfai, Krisztina Banfai, Zoltan Kellermayer, Attila Pap, Janet M. Lord, Judit E. Pongracz, Judit E. Pongracz, Krisztian Kvell, Krisztian Kvell   +10 more
doaj   +1 more source

Senescence in Mesenchymal Stem Cells: Functional Alterations, Molecular Mechanisms, and Rejuvenation Strategies

Frontiers in Cell and Developmental Biology, 2020
Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and differentiation. There is increasing evidence of the therapeutic value of MSCs in various clinical situations, however, these cells gradually lose their regenerative ...
Jing Liu, Jing Liu, Yue Ding, Zhongmin Liu, Zhongmin Liu, Xiaoting Liang, Xiaoting Liang   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Modulating the rejuvenation in a Al75Mg25 metallic glass by multiple recovery annealing treatment

Journal of Materials Research and Technology
Rejuvenation presents a promising way to improve the plasticity of metallic glasses. How modulating the degree of rejuvenation of metallic glasses remains a challenging issue. Here, based on the molecular dynamics simulation, we investigate the evolution
Xuelian Li, Chengyong Zhong, Xin Jin, Dongmei Li, Yueqi Li, Baoan Sun, Peng Yu   +6 more
doaj   +1 more source