Results 61 to 70 of about 40,752 (251)

Why Rejuvenation Attempts Often Lead to Cancer and Why Cyclic Rejuvenation Is Better: A Simple Qualitative Explanation [PDF]

open access: yes, 2022
Since the 1960s, biologists have shown that, contrary to the previous belief that ageing is irreversible, many undesirable biological effects of ageing can be reversed. First attempts to perform this reversal on living creatures were not fully successful:
Kreinovich, Vladik, Kosheleva, Olga
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Evolution of cell therapies derived from adipose tissue: historical perspectives, current development trends and future directions

open access: yesBiology Direct
Over the last few decades, adipose tissue has attracted increasing attention in the field of regenerative medicine, thanks to discoveries related to its regenerative, anti-inflammatory, and pro-angiogenic properties.
Silvia Gandolfi   +7 more
doaj   +1 more source

Analysis of Software Aging in a Web Server [PDF]

open access: yes
A number of recent studies have reported the phenomenon of “software aging”, characterized by progressive performance degradation and/or an increased occurrence rate of hang/crash failures of a software system due to the exhaustion of operating system ...
Liz, Lei   +3 more
core  

Nonsurgical Lip and Eye Rejuvenation Techniques

open access: yes, 2016
This book offers clinical physicians and plastic surgeons a detailed and comprehensive overview of the nonsurgical techniques used for rejuvenation of the lips and eyes.
Tosti, Antonella   +2 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

In Vitro and In Vivo Assessment of an Innovative Peeling System with Azelaic and Tranexamic Acids for Targeted Hyperpigmentation Reduction

open access: yesDermatology and Therapy
Introduction Melanin, derived from tyrosine, plays a pivotal role in skin pigmentation through melanogenesis. Disruptions in this process lead to hyperpigmentation, a condition affecting skin tone and quality of life.
Russell Wong   +6 more
doaj   +1 more source

Elastostatic loading rejuvenation behavior in bulk metallic glasses and its origin: A review

open access: yesJournal of Materials Research and Technology
Bulk metallic glasses (BMGs) that exhibit superior properties compared to their crystalline counterparts, such as high strength, excellent corrosion resistance and good magnetic properties, are emerging as advanced engineering materials.
Seyyedeh Maryam Mirhashemi   +1 more
doaj   +1 more source

Vaginal rejuvenation: current perspectives

open access: yes, 2017
Giussy Barbara,1 Federica Facchin,2 Laura Buggio,3 Daniela Alberico,3 Maria Pina Frattaruolo,3 Alessandra Kustermann1 1Department of Obstetrics and Gynecology, Service for Sexual and Domestic Violence (SVSeD), Fondazione IRCCS Ca’ Granda, Ospedale
Frattaruolo MP   +5 more
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

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