Results 201 to 210 of about 1,855,106 (245)

Childhood brain tumours instruct cranial haematopoiesis and immunotolerance

open access: yes
Cooper E   +26 more
europepmc   +1 more source

The opposite effects of stringent response on phage infection of <i>Pseudomonas putida</i>. [PDF]

open access: yesMicrolife
Lewańczyk AC   +5 more
europepmc   +1 more source

Therapeutic targeting of FOSL1 and RELA-dependent transcriptional mechanisms to suppress pancreatic cancer metastasis. [PDF]

open access: yesCell Death Dis
Aggrey-Fynn JE   +8 more
europepmc   +1 more source

NF-κB RelA Phosphorylation Regulates RelA Acetylation [PDF]

open access: yesMolecular and Cellular Biology, 2005
The nuclear functions of NF-kappaB p50/RelA heterodimers are regulated in part by posttranslational modifications of its RelA subunit, including phosphorylation and acetylation. Acetylation at lysines 218, 221, and 310 differentially regulates RelA's DNA binding activity, assembly with IkappaBalpha, and transcriptional activity.
Lin-Feng Chen   +2 more
exaly   +3 more sources
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Combinatorial Selection and Edited Combinatorial Selection of Phosphorothioate Aptamers Targeting Human Nuclear Factor-κB RelA/p50 and RelA/RelA

Biochemistry, 2004
Nuclear factor-kappaB (NF-kappaB) transcription factors are important in regulating the immune response and play critical roles in the pathogenesis of chronic inflammatory diseases and a variety of human cancers. Agents that target specific NF-kappaB dimers may serve as therapeutic agents for the prevention of pathogenic immune responses.
Suzanne E, Bassett   +8 more
openaire   +2 more sources

Nonsense and insertion mutants in the relA gene of E. coli: Cloning relA

Cell, 1978
We have made use of lysogens of a specialized transducing bacteriophage, lambdapyrG+ relA+, to select nonsense (relAnon) and insertion (relAins) mutations in the relA gene. Three independent relAnon mutants were isolated on the phage. In all three, the relaxed phenotype was suppressed by supD, supE, supF or sup6.
J D, Friesen, G, An, N P, Fiil
openaire   +2 more sources

Regulation of the RelA (p65) transactivation domain

Biochemical Society Transactions, 2008
The RelA (p65) NF-κB (nuclear factor κB) subunit contains an extremely active C-terminal transcriptional activation domain, required for its cellular function. In the present article, we review our knowledge of this domain, its modifications and its known interacting proteins.
O'Shea, John M., Perkins, Neil D.
openaire   +3 more sources

ChemInform Abstract: BENZALPHTHALIMIDINES AND RELA

Chemischer Informationsdienst, 1978
AbstractDas Chlorphthalsäureanhydrid (I) reagiert mit der Essigsäure (II) zu den isomeren Chlorbenzalphthaliden (IIIa) und (IIIb), die jeweils in Gegenwart von Alkali zu dem Indandion (IV) isomerisieren.
A. M. ISLAM   +2 more
openaire   +1 more source

RELA/NEAT1/miR‐302a‐3p/RELA feedback loop modulates pancreatic ductal adenocarcinoma cell proliferation and migration

Journal of Cellular Physiology, 2018
AbstractPancreatic ductal adenocarcinoma (PDAC) remains a challenging malignancy due to distant metastasis. RELA, a major component of the NF‐κB pathway, could serve as an oncogene through activating proliferation or migration‐related gene expression, including NEAT1, a well‐known oncogenic long noncoding RNA.
Zhen Luo   +7 more
openaire   +2 more sources

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