Results 191 to 200 of about 125,603 (234)

Pharmacological Modulation of Injury-Induced Vascular Remodeling by Colchicine: An Integrated Experimental and Network-Based Analysis. [PDF]

Biomedicines
Onar LC, Guner E, Yumun HNA, Dindar H, Yilmaz I, Yumun G.   +5 more
europepmc   +1 more source

NF-κB-driven lymphangiogenesis affects kidney function via a VEGFR-3-mediated pathway. [PDF]

JCI Insight
Melkonian AL, Traylor AM, Zmijewska AA, Moore KH, Ghajar-Rahimi G, Esman S, Jiang Y, Jang H, Mehrara BJ, Lee TC, George JF, Agarwal A.   +11 more
europepmc   +1 more source

Lnc1267-hnRNP U interaction promotes radioresistance by inhibiting apoptosis via attenuated RelA/p65 Ser536 phosphorylation. [PDF]

Cell Mol Life Sci
Qi Z, Fan Y, Liu X, Cai D, Lin C, Li Y, Zhang H, Jia M, Han J, Mo Y, Zhu M, Shen L, Wang Q, Wang Z.   +13 more
europepmc   +1 more source

DRP1 induces neuroinflammation via transcriptional regulation of NF-ĸB. [PDF]

Nat Commun
Lai Y, Fan RZ, Brown HJ, Salehe SS, Tieu EK, Tieu K.   +5 more
europepmc   +1 more source

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Nonsense and insertion mutants in the relA gene of E. coli: Cloning relA

Cell, 1978
We have made use of lysogens of a specialized transducing bacteriophage, lambdapyrG+ relA+, to select nonsense (relAnon) and insertion (relAins) mutations in the relA gene. Three independent relAnon mutants were isolated on the phage. In all three, the relaxed phenotype was suppressed by supD, supE, supF or sup6.
J D, Friesen, G, An, N P, Fiil
openaire   +2 more sources

Combinatorial Selection and Edited Combinatorial Selection of Phosphorothioate Aptamers Targeting Human Nuclear Factor-κB RelA/p50 and RelA/RelA

Biochemistry, 2004
Nuclear factor-kappaB (NF-kappaB) transcription factors are important in regulating the immune response and play critical roles in the pathogenesis of chronic inflammatory diseases and a variety of human cancers. Agents that target specific NF-kappaB dimers may serve as therapeutic agents for the prevention of pathogenic immune responses.
Suzanne E, Bassett, Susan M, Fennewald, David J, King, Xin, Li, Norbert K, Herzog, Robert, Shope, Judy F, Aronson, Bruce A, Luxon, David G, Gorenstein   +8 more
openaire   +2 more sources

Regulation of the RelA (p65) transactivation domain

Biochemical Society Transactions, 2008
The RelA (p65) NF-κB (nuclear factor κB) subunit contains an extremely active C-terminal transcriptional activation domain, required for its cellular function. In the present article, we review our knowledge of this domain, its modifications and its known interacting proteins.
O'Shea, John M., Perkins, Neil D.
openaire   +3 more sources

ChemInform Abstract: BENZALPHTHALIMIDINES AND RELA

Chemischer Informationsdienst, 1978
AbstractDas Chlorphthalsäureanhydrid (I) reagiert mit der Essigsäure (II) zu den isomeren Chlorbenzalphthaliden (IIIa) und (IIIb), die jeweils in Gegenwart von Alkali zu dem Indandion (IV) isomerisieren.
A. M. ISLAM, A. M. S. EL‐SHERIEF, F. A. EAD   +2 more
openaire   +1 more source

Genomic structure and chromosome location of the mouse RelA p65 gene (Rela).

Cytogenetics and cell genetics, 2000
The RelA (p65) subunit of transcription factor NF-kappaB plays a critical role in development, and rela(-/-) knockout mice die in utero from massive liver apoptosis. Only partial sequences of the mouse Rela gene are available. We have determined the genomic structure of mouse Rela and promoter, and have mapped the gene to chromosome 19B1-3.
E R, Lemmer, J L, Welch, T, Tsai, C L, Keck-Waggoner, C, Huh, D B, Zimonjic, N C, Popescu, S S, Thorgeirsson   +7 more
openaire   +1 more source

Biosynthetic regulation of individual proteins in relA + and relA strains of Escherichia coli during amino acid starvation

Molecular and General Genetics MGG, 1976
An isogenic pair of Escherichia coli mutants (relA+ tufB valSts and relA1 tufB valSts) has been cultured at several temperatures to establish various degrees of limitation for valyl-tRNA synthetase. The biosynthetic rate of 16 identifiable proteins, most of which are components of the transcription and translation apparatus, was measured by pulse ...
S, Reeh, S, Pedersen, J D, Friesen
openaire   +2 more sources