Results 171 to 180 of about 153,606 (275)

A Gene Expression Tumor Signature Optimizing Partial Area‐Under‐the‐Curve (pAUC) to Improve Specificity for Indolent Prostate Cancer

The Prostate, Volume 86, Issue 9, Page 1075-1082, June 15, 2026.
ABSTRACT Purpose A key clinical challenge in prostate cancer is the identification and validation of biomarkers with high specificity for indolent long‐term outcomes. We applied a novel statistical method to identify tumor transcriptomic biomarkers that optimally predicted patients with low metastatic potential.
Travis A. Gerke, Svitlana Tyekucheva, Konrad H. Stopsack, Christopher J. Sweeney, Rosina T. Lis, Elizabeth N. Westling, Massimo Loda, Meir J. Stampfer, Kathryn L. Penney, Giovanni Parmigiani, Lorelei A. Mucci   +10 more
wiley   +1 more source

Epigenetic context defines the transcriptional activity of canonical and noncanonical NF-κB signaling in pancreatic cancer. [PDF]

Cell Death Discov
Aggrey-Fynn JE, Busch J, Saul D, Rajput A, Willecke K, Manjunath M, Klimt N, Rajendran K, Schacherer N, Ge W, Thiel J, Abdelrahman A, Truty MJ, Dong M, Johnsen SA.   +14 more
europepmc   +1 more source

GTP pyrophosphokinase (relA) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Quercetin attenuates skin inflammation and fibrosis in systemic sclerosis by targeting the RELA/c-Jun axis to suppress th17 cell responses. [PDF]

Front Immunol
Kong X, Leong H, Du M, Yang J, Lai J, Dong Z, Hu M, Gu Y, Li Y, Tan Q, Chu H, Liu Q, Ma Y, Xu W, Li S, Chen Y, Chen D, Chen Y, Lu W, Zhu J, Wang J, Wang L.   +21 more
europepmc   +1 more source

The NF‐κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Nuclear Factor‐kappa B (NF‐κB) is a master transcriptional regulator orchestrating critical cellular processes, predominantly immunity and inflammation. However, its aberrant constitutive activation has emerged as a unifying pathogenetic hallmark across diverse malignancies, autoimmune disorders, and chronic inflammatory diseases.
Bherouz Pourdad, Arash Pourdad
wiley   +1 more source

Endoscopic nipple-sparing mastectomy with immediate DIEP flap reconstruction following neoadjuvant chemotherapy for multifocal HER2-positive breast cancer: a case report. [PDF]

J Surg Case Rep
Mathan PJ, Gandhirajan K, Bose JC, Arumugam S, Manivasagam P, Kamaldeen S.   +5 more
europepmc   +1 more source

RelA-Associated Inhibitor [PDF]

, 2020
openaire   +1 more source

Maternal Paradox: When Nurturer Meets the Knife, Living Organ Donation From Daughters to Mothers in Türkiye

Sociology Lens, Volume 39, Issue 2, Page 207-223, June 2026.
ABSTRACT This article uses the case of living organ donation from daughters to mothers in Türkiye to examine how maternal subjectivities are constructed, enacted, and transformed within specific cultural contexts. In Türkiye, motherhood is both culturally idealized and politically reinforced as the moral core of womanhood.
Sezen Demirhan, İlknur Gürses Köse
wiley   +1 more source

RELA as a Diagnostic Biomarker for Parkinson's Disease by Integrating Ferroptosis, Lipid Metabolism, and Neuroinflammation. [PDF]

Inflammation
Chen Q, Jing Y, Bu W, Zhang J, Liu W, Shi C, Liu C, Su D.   +7 more
europepmc   +1 more source

Molecular Clocks in Translational Roadmap for Circadian‐Based Therapeutics in Lung Diseases

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
High‐amplitude circadian oscillations maintain lung immune and epithelial homeostasis. Chronic inflammation dampens peripheral clock amplitude, driving chronodisruption, barrier dysfunction, and remodeling. Clock‐targeted therapies re‐entrain the lung circadian clock, restore rhythmic immune resolution, and promote functional lung repair.
Kingshuk Panda, Renu Khasa, Srinivasan Chinnapaiyan, Saurabh Aggarwal, Irfan Rahman, Hoshang Unwalla   +5 more
wiley   +1 more source