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Leprosy is unique in terms of the nature of the causative organism (Mycobacterium leprae), the chronicity of the disease, its prolonged treatment and the definitions of "cure" and "relapse." The principal mode of assessing the efficacy of therapeutic regimens in leprosy is the "relapse rate." There are wide variations in estimates of relapse rates ...
Kaimal, Sowmya, Thappa, Devinder Mohan
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Objectives: The purpose of the present study was to evaluate skeletal stability after mandibular advancement with bilateral sagittal split osteotomy. Material and Methods: Twenty-six patients underwent single-jaw bilateral sagittal split osteotomy ...
Jens Hartlev+3 more
doaj +1 more source
Effectiveness of delayed-release dimethyl fumarate on patient-reported outcomes and clinical measures in patients with relapsing-remitting multiple sclerosis in a real-world clinical setting: PROTEC. [PDF]
Ensaio clínico PROTEC, Protocolo nº 109MS408Abstract BACKGROUND: Patient-reported outcomes (PRO) and clinical outcomes give a broad assessment of relapsing-remitting multiple sclerosis (RRMS) disease.
Berger, T+5 more
core +1 more source
Sun Exposure across the Life Course Significantly Modulates Early Multiple Sclerosis Clinical Course
BackgroundLow vitamin D and/or sun exposure have been associated with increased risk of multiple sclerosis (MS) onset. However, comparatively, few studies have prospectively examined associations between these factors and clinical course.ObjectivesTo ...
Steve Simpson+28 more
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Acute myeloid leukemia (AML) with t(8;21) is a heterogeneous disease. Although the detection of minimal residual disease (MRD), which is indicated by RUNX1‐RUNX1T1 transcript levels, plays a key role in directing treatment, risk stratification needs to ...
Lu Yang+11 more
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Routine Clustering of Mobile Sensor Data Facilitates Psychotic Relapse Prediction in Schizophrenia Patients [PDF]
We aim to develop clustering models to obtain behavioral representations from continuous multimodal mobile sensing data towards relapse prediction tasks. The identified clusters could represent different routine behavioral trends related to daily living of patients as well as atypical behavioral trends associated with impending relapse.
arxiv +1 more source
Psychotic Relapse Prediction in Schizophrenia Patients using A Mobile Sensing-based Supervised Deep Learning Model [PDF]
Mobile sensing-based modeling of behavioral changes could predict an oncoming psychotic relapse in schizophrenia patients for timely interventions. Deep learning models could complement existing non-deep learning models for relapse prediction by modeling latent behavioral features relevant to the prediction.
arxiv
Plasmodium vivax is a major cause of febrile illness in endemic areas of Asia, Central and South America, and the horn of Africa. P. vivax infections are characterized by relapses of malaria arising from persistent liver stages of the parasite (hypnozoites), which can be prevented currently only by 8-aminoquinoline anti-malarials. Tropical P.
White, N, Imwong, M
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Management of Relapsed and Relapsed Refractory Myeloma
Studies of bortezomib, thalidomide, and lenalidomide have shown promising clinical activity in relapsed/refractory multiple myeloma (MM). Bortezomib alone and in combination with other agents is associated with high response rates, consistently high rates of complete response, and a predictable and manageable profile of adverse events.
Kastritis, E.+3 more
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Review on Acute Relapse of Spinal Cord Infarction: A Case Report
Objective: To present a case of relapsed spinal cord infarction (SCI) as an acute spinal emergency in an in-patient elderly male patient. Methods: This report presents a case of an in-patient 84 years-old man who was admitted due to acute paraparesis ...
Maria Sofia Cotelli, Filippo Manelli
doaj +1 more source