Results 101 to 110 of about 41,565 (267)

Understanding progression in primary progressive multiple sclerosis: a longitudinal clinical and magnetic resonance imaging study

, 2010
The work in this thesis applies magnetization transfer imaging (MTI) and conventional MRI measures (brain volume, T2 lesion load and enhancing lesions) to investigate the mechanisms underlying progression in primary progressive multiple sclerosis ...
Khaleeli, Z.
core  

Neurofilament light as a prognostic marker in multiple sclerosis

, 2010
Relapsing-remitting multiple sclerosis has a variable prognosis and lacks a reliable laboratory prognostic marker. Our aim in this study was to investigate the association between neurofilament light levels in cerebrospinal fluid in early multiple ...
Sundström, Peter,, Salzer, Jonatan,, Svenningsson, Anders,   +2 more
core   +1 more source

Cognitive trajectories in relapsing-remitting multiple sclerosis: a longitudinal 6-year study

, 2020
Background: Information concerning longitudinal cognitive trajectories in multiple sclerosis (MS) is relatively scarce. Moreover, it is unclear which factors are associated with cognitive decline and what is the clinical impact of cognitive impairment ...
Pimentel-Silva, Luciana Ramalho, Damasceno, Alfredo, Cendes, Fernando, Damasceno, Benito Pereira   +3 more
core   +1 more source

Circadian Activity Rhythm in Early Relapsing-Remitting Multiple Sclerosis [PDF]

, 2019
While relapsing-remitting is the most prevalent course of multiple sclerosis, the prognostic/predictive markers of the worsening of symptomatology are still debated.
Lugaresi, Alessandra, Federico Camilli, Alessandra Lugaresi, Lorenzo Tonetti, Sara Giovagnoli, Giovagnoli, Sara, Camilli, Federico, Vincenzo Natale, Tonetti, Lorenzo, Natale, Vincenzo   +9 more
core   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Non-traumatic Acute Epidural Hematoma in Multiple Sclerosis Treated With Fingolimod

Frontiers in Neurology, 2019
Fingolimod acts as a functional antagonist of the sphingosine-1-phosphate receptor and is widely used for relapsing-remitting multiple sclerosis (MS).
Ryoko Fukai, Keita Takahashi, Hiroyuki Abe, Yuichi Higashiyama, Hiroshi Doi, Hideyuki Takeuchi, Fumiaki Tanaka   +6 more
doaj   +1 more source

Advances in the treatment of relapsing - Remitting multiple sclerosis

Biomedical Journal, 2014
This article reviews and discusses the approved and emerging therapies for multiple sclerosis (MS). MS is a chronic and disabling immune-mediated disease of the central nervous system (CNS) that affects mainly young adults. MS imposes a huge economic burden on healthcare systems and the society.
Radu Tanasescu, Carolina Ionete, I-Jun Chou, Cris S Constantinescu   +3 more
openaire   +3 more sources

Estimation of annual probabilities of changing disability levels in Australians with relapsing-remitting multiple sclerosis

, 2019
BACKGROUND: Transition probabilities are the engine within many health economics decision models. However, the probabilities of progression of disability due to multiple sclerosis (MS) have not previously been estimated in Australia.
Ahmad, Hasnat, Broadley, Simon, Lucas, Robyn M, van der Mei, Ingrid, Taylor, Bruce, Clarke, Philip M, Palmer, Andrew J, Valery, Patricia, Lechner-Scott, Jeannette, Ponsonby, Anne-Louise, Dwyer, Terry, Dear, Keith, Blizzard, Leigh, Simpson, Steve, et al.   +14 more
core   +1 more source

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source