Results 121 to 130 of about 41,565 (267)

Associations of cannabis use, tobacco use and co‐use with brain volume: A systematic review and meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer, Tom P. Freeman, Martine Skumlien, Esther Walton, Thomas Lancaster, Jorien L. Treur, Valentina Lorenzetti, Anna K. M. Blackwell, Chloe Burke, Richie J. Carr, Constantinos Constantinides, Maisie Cox, Sarah Dance, Shadi Daryan, Sorcha Hamilton, Tom Jenkins, Gemma M. J. Taylor   +16 more
wiley   +1 more source

Risk of secondary progressive multiple sclerosis: A longitudinal study.

, 2020
BACKGROUND: The risk factors for conversion from relapsing-remitting to secondary progressive multiple sclerosis remain highly contested. OBJECTIVE: The aim of this study was to determine the demographic, clinical and paraclinical features that influence
Jun, Jae-Kwan, Spelman, Tim, Pucci, Eugenio, Verheul, Freek, Fragoso, Yara, Yamout, Bassem, Al-Harbi, Talal, Bergamaschi, Roberto, Gray, Orla, Butzkueven, Helmut, Prat, Alexandre, Turkoglu, Recai, McCombe, Pamela, Grand'Maison, Francois, Lugaresi, Alessandra, Alroughani, Raed, Terzi, Murat, Petersen, Thor, Slee, Mark, Shaw, Cameron, Hughes, Jordana, Barnett, Michael, Moore, Fraser, Trojano, Maria, Vucic, Steve, Olascoaga, Javier, Horakova, Dana, Saladino, Maria Laura, Altintas, Ayse, Sanchez-Menoyo, Jose Luis, Deri, Norma, Kubala Havrdova, Eva, Skibina, Olga, Ozakbas, Serkan, Iuliano, Gerardo, Cristiano, Edgardo, Taylor, Bruce, Ferraro, Diana, Fambiatos, Adam, Izquierdo, Guillermo, Van Pesch, Vincent, Ampapa, Radek, Van Wijmeersch, Bart, Lechner-Scott, Jeannette, Granella, Franco, Sidhom, Youssef, Boz, Cavit, Hupperts, Raymond, Spitaleri, Daniele, Girard, Marc, Solaro, Claudio, Duquette, Pierre, Soysal, Aysun, Singhal, Bhim, Shuey, Neil, Hodgkinson, Suzanne, Csepany, Tunde, Havrdova, Eva Kubala, Jokubaitis, Vilija, Prevost, Julie, Grammond, Pierre, Kalincik, Tomas, Sola, Patrizia, van der Walt, Anneke   +63 more
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Frailty and Fitness in Older Adults With Acute Myeloid Leukemia: From Chronological Age to Multiparametric Assessment

European Journal of Haematology, EarlyView.
ABSTRACT Acute Myeloid Leukemia predominantly affects older adults, who often present with comorbidities, functional impairment, and frailty, limiting eligibility for intensive chemotherapy or allogeneic transplantation. Historically, treatment options were restricted to hypomethylating agents, low‐dose cytarabine, hydroxyurea, or supportive care, with
Antonella Bruzzese, Enrica Antonia Martino, Santino Caserta, Maria Eugenia Alvaro, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Ernesto Vigna, Massimo Gentile   +11 more
wiley   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

Comparison of the Patients Suffering from Relapsing-Remitting Multiple Sclerosis with Healthy Individuals regarding Serum Selenium and Zinc Levels

پزشکی بالینی ابن سینا, 2020
Background and Objective: Multiple sclerosis is an autoimmune disease of the central nervous system that causes demyelination and axonal damage. There are contradictory results regarding the effects of zinc and selenium on the prevention or reduction of ...
Ali Asghar Vahidinia, Mehrdokht Mazdeh, Salahadin Adman, Zahra Cheraghi   +3 more
doaj  

Oral available agents in the treatment of relapsing remitting multiple sclerosis an overview of merits and culprits

, 2013
Jan Thöne, Gisa Ellrichmann Department of Neurology, St Josef-Hospital Bochum, Ruhr-University Bochum, Bochum, Germany Abstract: Multiple sclerosis (MS) is a chronic immunological disease of the central nervous system characterized by early ...
Thöne J, Ellrichmann G
core  

Endogenous task shift processes in relapsing-remitting multiple sclerosis

, 2004
This paper reports a study that was aimed to evaluate executive functions in relapsing-remitting multiple sclerosis patients. The groups tested comprised 22 relapsing-remitting multiple sclerosis patients, and 22 non-brain damaged controls.
TOSO V., MELIGRANA L., STABLUM, FRANCA, BORTOLON F., SGARAMELLA, TERESA MARIA   +4 more
core   +1 more source

Neural correlates of pure apathy in multiple sclerosis: An exploratory neuroimaging study

Journal of Neuropsychology, EarlyView.
Abstract Pure apathy is relatively common in people with Multiple Sclerosis (PwMS), but its neural mechanisms remain unexplored. Therefore, we investigated the neural correlates of pure apathy in PwMS, differentiating it from depression. Sixty‐two PwMS underwent neuropsychological assessments and Magnetic Resonance Imaging scans.
Valentina Torchia, Vera Gramigna, Mariachiara Gaita, Daniele Spitaleri, Antonio Costanzo, Liana Palermo, Florindo d'Onofrio, Simona Raimo   +7 more
wiley   +1 more source

Beta-interferons in multiple sclerosis: A single center experience in India

Annals of Indian Academy of Neurology, 2010
Background: Indian-Asian multiple sclerosis behaves somewhat differently from Western disease. It is not known if the response to β-interferon is also different.
Gupta Salil, Varadarajulu R, Ganjoo R
doaj