Results 131 to 140 of about 4,730,453 (227)
ABSTRACT Purpose QQ, a recently proposed oxygen extraction fraction (OEF) mapping technique combining quantitative susceptibility mapping (QSM) and quantitative blood oxygen level‐dependent (qBOLD) (QSM + qBOLD = QQ), generates OEF maps noninvasively from a single routine MRI sequence, without requiring vascular challenges used in other OEF approaches.
Tian Qiu +8 more
wiley +1 more source
Multiple sclerosis: Intrathecal inflammation mediates mood in relapsing–remitting multiple sclerosis
In Brief comment on original article Rossi, S. et al. Neuroinflammation drives anxiety and depression in relapsing–remitting multiple sclerosis. Neurology http://dx.doi.org/10.1212/ WNL.0000000000004411 (2017)A new study has revealed that subclinical ...
Patel, Mitesh
core +2 more sources
ABSTRACT Purpose In the spinal cord (SC), multi‐echo gradient echo (ME‐GRE) increases gray (GM) and white matter (WM) contrast and improves sensitivity to lesions in people with multiple sclerosis (pwMS). However, SC ME‐GRE is susceptible to breathing‐induced field fluctuations, causing ghosting artifacts and signal loss.
Alicia E. Cronin +13 more
wiley +1 more source
The Maintenance of Dysmyelinated Small‐Diameter Axons by 14‐3‐3s in the Central Nervous System
Dysmyelinated small‐diameter axons are maintained in teneurin‐4 deficient mice at the age of 1 year, while axonal damage is observed. 14‐3‐3s are highly expressed and suppress the progression of the damage in these axons. ABSTRACT In the central nervous system, myelin formed around nerve axons by oligodendrocyte enables efficient conduction of action ...
Nanako Yamada +15 more
wiley +1 more source
Cristina Guarnera, Placido Bramanti, Emanuela Mazzon IRCCS Centro Neurolesi “Bonino-Pulejo”, Messina, Italy Abstract: In the therapeutic scenario of disease-modifying therapies for relapsing–remitting multiple sclerosis, the ...
Guarnera C, Bramanti P, Mazzon E
doaj
Multiple Sclerosis and Viruses: « Liaisons Dangereuses »
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina +11 more
wiley +1 more source
Is it time to target no evident disease activity (NEDA) in multiple sclerosis? [PDF]
Marta, M +5 more
core +1 more source
Health Literacy and Unmet Needs in Patients With Multiple Sclerosis: A Cross‐Sectional Study
ABSTRACT Aims To identify a correlation between unmet needs and HL levels in people with Multiple Sclerosis (pwMS) and to evaluate how sociodemographic characteristics influence HL levels and unmet needs. Design A cross‐sectional study. Methods The study was conducted using a questionnaire including the HLS19‐Q12 to assess HL and the Long‐term Unmet ...
Francesco Pastore +6 more
wiley +1 more source
Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source
The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci +25 more
wiley +1 more source

