Results 91 to 100 of about 6,056,278 (299)

Exploring Factors Influencing Patients’ Intention to Adopt Generative AI on Online Healthcare Platforms

open access: yesJournal of Theoretical and Applied Electronic Commerce Research
The development of generative AI has disrupted various fields, and the field of online healthcare is no exception. However, there is a lack of research on patients’ intention to adopt generative AI on online healthcare platforms.
Yu Li, Tian Shen, Shuyi Yang, Xi Chen
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Working Overtime and Turnover Intention Among Chinese Social Workers: Roles of Organizational Identity and Individual Income

open access: yesSAGE Open
Although the negative effects of employee overtime have received academic attention, the relationship between overtime work and social workers’ turnover intention and its underlying mechanisms have been less studied.
Weidong Huo, Bolin Shi
doaj   +1 more source

Desire and Behavioral Intention in Sharing Accommodation: Hedonic and Economic Benefits as Mediators and Perceived Risk and Materialism as Moderators

open access: yesTourism and Hospitality
The present study aims to explore the factors that warrant consumers’ behavioral intention through sharing accommodation. A multilayered conceptual model is developed to analyze the impact of desire on behavioral intention through hedonic and economic ...
Pooja Goel, Satyanarayana Parayitam
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Factors affecting entrepreneurial intention levels [PDF]

open access: yes
Entrepreneurship is becoming a very relevant instrument to promote economic growth and development in different regional and national economies.
Francisco Liñán   +2 more
core  

Relationship of knowledge sharing and innovation intention on the continuous quality improvement in university setting

open access: yes
This study assessed the changed knowledge sharing system and innovative intention towards continuous quality improvement in one university system in the Philippines.
Niño Philip L. Perculeza
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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