Results 81 to 90 of about 740,069 (270)

CBCT-to-CT synthesis with a single neural network for head-and-neck, lung and breast cancer adaptive radiotherapy

, 2019
Purpose: CBCT-based adaptive radiotherapy requires daily images for accurate dose calculations. This study investigates the feasibility of applying a single convolutional network to facilitate CBCT-to-CT synthesis for head-and-neck, lung, and breast ...
Berg, Cornelis AT van den, Houweling, Anette C, Kotte, Alexis NTJ, Maspero, Matteo, Savenije, Mark HF, van Heijst, Tristan CF, Verhoeff, Joost JC   +6 more
core   +1 more source

Individualisation of time-motion analysis : a method comparison and case report series [PDF]

, 2014
© Georg Thieme Verlag KG. This study compared the intensity distribution of time-motion analysis data, when speed zones were categorized by different methods.
Abt, G., Barrett, S., Bray, J., Hunter, F., Lovell, R., Madden, J., Smith, M., Towlson, C.   +7 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Relative dose intensity of first-line triplet chemotherapy in metastatic colorectal cancer

Digestive and Liver Disease
Relative dose intensity (RDI) is a measurement of chemotherapy (CT) dose defined as the actual dose received divided by the standard calculated dose during a set period. The study objective was to assess the impact of a RDI ≥ 80% on response and survival of patients treated in first line CT by FOLFOXIRI or FOLFIRINOX ± Bevacizumab (BV) for an ...
Julien Hoba, Adrien Grancher, Vincent Hautefeuille, Anthony Turpin, Karine Bouhier-Leporrier, Marie-Pierre Galais, Anne-Laure Bignon, Aude Di Fiore, Romain Desgrippes, Laurent Miglianico, Benoit Avisse, Mathieu Baconnier, You-Heng Lam, Marie Dutherage, David Sefrioui, Karine Le Malicot, Jean-Marc Phelip, Pierre Michel, André Gillibert, Frédéric Di Fiore   +19 more
openaire   +2 more sources

Comparing The Effects Of Menthol Status On The Behavioral Pharmacology Of Smoking Reduced Nicotine Content Cigarettes [PDF]

, 2017
Introduction: An active area of tobacco regulatory science research focuses on examining the effects of varying the nicotine content of cigarettes as part of a potential national policy to lower their nicotine content levels to reduce addiction potential.
Davis, Danielle
core   +1 more source

Development and operation of a pixel segmented liquid-filled linear array for radiotherapy quality assurance

, 2004
A liquid isooctane (C$_{8}$H$_{18}$) filled ionization linear array for radiotherapy quality assurance has been designed, built and tested. The detector consists of 128 pixels, each of them with an area of 1.7 mm $\times$ 1.7 mm and a gap of 0.5 mm.
A Iglesias, A Pazos, Belletti S, Boag J W, Debye P, Eberle K, F Gómez, Fowler J F, J Mosquera, J Pardo, J Pena, J Sendón, Johansson B, L Franco, M Pombar, Martens C, Martens C, Pardo J, R Lobato, van Herk M, Wickman G   +20 more
core   +1 more source

Observations by human subjects on radiation- induced light flashes in fast-neutron, X-ray, and positive-pion beams [PDF]

, 1970
Exposure of human subjects to fast neutron beam to determine cause of light flashes observed by astronauts on lunar ...
Budinger, T. F., Lyman, J. T., Tobias, C. A.   +2 more
core   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The effect of the relative dose intensity of chemoradiotherapy on the effectiveness of therapy of locally advanced unresectable non-small cell lung cancer

Исследования и практика в медицине
The purpose of the study. To estimate the number of patients with the preservation of relative dose intensity (RDI) ≥ 80 % of first-line antitumor therapy in patients with unresectable non-small cell lung cancer (NSCLC), and to compare the effectiveness ...
A. E. Glukhareva, G. V. Afonin, I. V. Kolobaev, L. Yu. Grivtsova, S. A. Ivanov, A.  D.  Kaprin   +5 more
doaj   +1 more source