Results 61 to 70 of about 383,512 (276)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
3D relative pose estimation from distance-only measurements [PDF]
2007 IEEE/RSJ International Conference on Intelligent Robots and Systems, 2007 In this paper, we develop an algorithm for determining the relative position and attitude of two robots moving in 3D, using only dead-reckoning and inter-robot distance measurements. From the mechanical analogue of parallel manipulators, it is known that this problem has 40 solutions when six distance measurements are available. These general solutions
null Nikolas Trawny +3 more
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
A Systematic Review of Recent Deep Learning Approaches for 3D Human Pose Estimation
Journal of Imaging, 2023 Three-dimensional human pose estimation has made significant advancements through the integration of deep learning techniques. This survey provides a comprehensive review of recent 3D human pose estimation methods, with a focus on monocular images ...
Amal El Kaid, Karim Baïna
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Light Field Rectification Based on Relative Pose Estimation
IEEE Transactions on Instrumentation and MeasurementHand-held light field (LF) cameras have unique advantages in computer vision such as 3D scene reconstruction and depth estimation. However, the related applications are limited by the ultra-small baseline, e.g., leading to the extremely low depth resolution in reconstruction.
Xiao Huo +3 more
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Relative Pose Estimation of an Uncooperative Target with Camera Marker Detection
AerospaceAccurate and robust relative pose estimation is the first step in ensuring the success of an active debris removal mission. This paper introduces a novel method to detect structural markers on the European Space Agency’s Environmental Satellite (ENVISAT)
Batu Candan, Simone Servadio
doaj +1 more source
A Factor Graph Approach to Multi-Camera Extrinsic Calibration on Legged Robots
, 2019 Legged robots are becoming popular not only in research, but also in industry, where they can demonstrate their superiority over wheeled machines in a variety of applications.
Camurri, Marco +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source