Results 81 to 90 of about 1,840,232 (265)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Micropower 'Relative Precision' 15 bit A/D Converter [PDF]

open access: yes, 2007
State of the art A/D converters are still critical in power-sensitive, battery-operated equipment like hearing aids. In this article, a new approach is presented that features excellent signal quality, 85 dB dynamic range equivalent to a 15-bit output word, 16 kHz sampling rate, 25 μW power consumption, and 0.54 mm2 chip area.
Grisoni, L.   +4 more
openaire  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Demonstration of plate analysis, an algorithm for precise relative astrometry

open access: yesJournal of Astronomical Telescopes, Instruments, and Systems
author's submit version, 31 pages, 11 figures, accepted for publication in Journal of Astronomical Telescopes, Instruments, and ...
Ohsawa, Ryou   +5 more
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

INFORMATION AND THE ADOPTION OF PRECISION FARMING [PDF]

open access: yes
This study examines the relationship between precision farming information sources and precision farming adoption. The analysis accounts for the fact that not all farmers are aware of precision farming techniques and that those who are aware may not be a
Daberkow, Stan G., McBride, William D.
core   +1 more source

High Precision Relative Motion Modelling.

open access: yes, 2006
There is an increasing interest in missions employing groups of satellites flying in formations and constellations. Such missions require highly autonomous and accurate orbit determination and control systems. The Disaster Monitoring Constellation (DMC) is an international consortium, consisting currently of four remote-sensing satellites equally ...
openaire   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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